C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dual specificity phosphatase 19
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000162999 DUSP19 9606 + 2:183078559-183100005 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000342619 DUSP19-002 183078559-183095899 protein_coding
  ENST00000354221 DUSP19-001 183078759-183100005 protein_coding
  ENST00000469344 DUSP19-003 183078989-183095903 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000354221
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000354221 0.363±0.00 0.563±0.00 0.586±0.00 0.590±0.26 0.757±0.08 0.546±0.15 0.833±0.30 0.216±0.04 0.560±0.00 0.338±0.00 0.127±0.00 0.429±0.35 0.295±0.19 1.337±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000Q8 CIL_0000Q8_0001 CGP 2:182909115-183100005
CIL_0000Q9 CIL_0000Q9_0001 CGP 2:183078559-183161680

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000188 IEA inactivation of MAPK activity
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0004860 ISS protein kinase inhibitor activity
GO:0005078 ISS MAP-kinase scaffold activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0006469 ISS negative regulation of protein kinase activity
GO:0006470 IBA:IEA protein dephosphorylation
GO:0007254 IBA JNK cascade
GO:0008138 IEA protein tyrosine/serine/threonine phosphatase activity
GO:0008330 IEA protein tyrosine/threonine phosphatase activity
GO:0008579 IBA JUN kinase phosphatase activity
GO:0016311 IEA dephosphorylation
GO:0016791 IEA phosphatase activity
GO:0030295 ISS protein kinase activator activity
GO:0031435 ISS mitogen-activated protein kinase kinase kinase binding
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0043410 ISS positive regulation of MAPK cascade
GO:0043507 ISS positive regulation of JUN kinase activity
GO:0043508 ISS negative regulation of JUN kinase activity
GO:0045860 ISS positive regulation of protein kinase activity
GO:0046329 ISS negative regulation of JNK cascade
GO:0046330 ISS positive regulation of JNK cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040490 dusp19a dual specificity phosphatase 19a protein_coding Danio_rerio
ENSDARG00000045200 dusp19b dual specificity phosphatase 19b protein_coding Danio_rerio
ENSMUSG00000027001 Dusp19 dual specificity phosphatase 19 protein_coding Mus_musculus

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