C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: excision repair cross-complementation group 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000163161 ERCC3 9606 - 2:127257290-127294176 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000285398 ERCC3-001 127257290-127294176 protein_coding
  ENST00000426778 ERCC3-005 127257290-127294145 nonsense_mediated_decay
  ENST00000445889 ERCC3-004 127257297-127294094 nonsense_mediated_decay
  ENST00000456257 ERCC3-011 127288673-127290275 protein_coding
  ENST00000460485 ERCC3-010 127289376-127290589 retained_intron
  ENST00000462306 ERCC3-002 127289696-127294137 retained_intron
  ENST00000490062 ERCC3-007 127292435-127294153 retained_intron
  ENST00000491292 ERCC3-006 127257297-127262882 retained_intron
  ENST00000494464 ERCC3-003 127286749-127294107 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000285398ENST00000426778ENST00000445889ENST00000456257ENST00000490062ENST00000491292
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000285398 4.596±0.00 6.516±0.00 1.390±0.00 5.308±1.24 3.813±1.99 3.822±0.18 3.743±2.39 4.385±3.28 3.848±1.82 1.422±0.34 5.821±2.23 9.008±3.30 7.778±2.21 20.871±2.40
ENST00000426778 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.553±0.00 N/A N/A N/A N/A
ENST00000445889 N/A N/A N/A N/A N/A N/A N/A 1.554±0.00 N/A N/A N/A N/A N/A N/A
ENST00000456257 N/A N/A N/A N/A N/A N/A N/A N/A 2.569±0.00 N/A N/A 19.190±0.00 8.196±0.00 30.566±0.00
ENST00000490062 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.951±0.00 N/A
ENST00000491292 N/A 1.296±0.00 N/A N/A N/A N/A N/A 0.622±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000439 IEA core TFIIH complex
GO:0000717 IMP nucleotide-excision repair, DNA duplex unwinding
GO:0000718 TAS nucleotide-excision repair, DNA damage removal
GO:0001666 IEA response to hypoxia
GO:0003677 TAS:IEA DNA binding
GO:0003684 NAS damaged DNA binding
GO:0004003 IEA ATP-dependent DNA helicase activity
GO:0004672 IDA protein kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005525 IEA GTP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005675 TAS holo TFIIH complex
GO:0006200 IEA ATP catabolic process
GO:0006265 IMP DNA topological change
GO:0006281 IMP DNA repair
GO:0006283 IDA transcription-coupled nucleotide-excision repair
GO:0006289 IMP:IEA nucleotide-excision repair
GO:0006360 TAS transcription from RNA polymerase I promoter
GO:0006361 TAS transcription initiation from RNA polymerase I promoter
GO:0006362 TAS transcription elongation from RNA polymerase I promoter
GO:0006363 TAS termination of RNA polymerase I transcription
GO:0006366 IMP transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006368 TAS transcription elongation from RNA polymerase II promoter
GO:0006370 TAS 7-methylguanosine mRNA capping
GO:0006468 IEA protein phosphorylation
GO:0006915 IMP apoptotic process
GO:0006979 IMP response to oxidative stress
GO:0008022 IPI protein C-terminus binding
GO:0008094 IMP DNA-dependent ATPase activity
GO:0008104 IMP protein localization
GO:0008134 IDA transcription factor binding
GO:0008353 IDA RNA polymerase II carboxy-terminal domain kinase activity
GO:0009411 IMP response to UV
GO:0009650 IEA UV protection
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0016787 IEA hydrolase activity
GO:0016887 IDA ATPase activity
GO:0032564 IEA dATP binding
GO:0033683 IMP nucleotide-excision repair, DNA incision
GO:0035315 IMP hair cell differentiation
GO:0042277 IEA peptide binding
GO:0043065 IDA positive regulation of apoptotic process
GO:0043138 IDA 3'-5' DNA helicase activity
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0047485 IPI protein N-terminus binding
GO:0050434 TAS positive regulation of viral transcription
GO:1901990 IMP regulation of mitotic cell cycle phase transition

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002402 ercc3 excision repair cross-complementing rodent repair deficiency, complementation group 3 protein_coding Danio_rerio
ENSMUSG00000024382 Ercc3 excision repair cross-complementing rodent repair deficiency, complementation group 3 protein_coding Mus_musculus

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