C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: excision repair cross-complementing rodent repair deficiency, complementation group 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024382 Ercc3 10090 + 18:32240300-32270151 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025241 Ercc3-001 32240300-32270151 protein_coding
  ENSMUST00000129023 Ercc3-003 32257269-32270091 processed_transcript
  ENSMUST00000142213 Ercc3-002 32240354-32270151 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025241ENSMUST00000129023ENSMUST00000142213
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025241 14.041±2.19 8.551±1.35 12.476±1.93 10.645±2.63 9.957±1.71 13.389±0.83 5.478±0.61 10.700±1.17 7.120±1.37 13.376±0.72 3.982±0.48 15.823±1.46 15.590±3.32 14.919±0.90
ENSMUST00000129023 N/A N/A N/A N/A 5.025±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000142213 N/A 1.337±0.00 N/A N/A 1.319±0.00 1.522±0.00 0.753±0.00 N/A N/A N/A 0.810±0.00 1.900±0.06 1.742±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000439 IEA core TFIIH complex
GO:0000717 IEA nucleotide-excision repair, DNA duplex unwinding
GO:0001666 IEA response to hypoxia
GO:0003677 IEA DNA binding
GO:0004672 ISS protein kinase activity
GO:0005515 IEA protein binding
GO:0005525 IEA GTP binding
GO:0005634 IEA nucleus
GO:0005675 ISS holo TFIIH complex
GO:0006200 IEA ATP catabolic process
GO:0006265 ISS DNA topological change
GO:0006281 IEA DNA repair
GO:0006283 ISS transcription-coupled nucleotide-excision repair
GO:0006366 ISS transcription from RNA polymerase II promoter
GO:0006468 IEA protein phosphorylation
GO:0006915 ISS apoptotic process
GO:0006979 IEA response to oxidative stress
GO:0008022 IEA protein C-terminus binding
GO:0008094 ISS DNA-dependent ATPase activity
GO:0008104 IEA protein localization
GO:0008134 IEA transcription factor binding
GO:0008353 ISS RNA polymerase II carboxy-terminal domain kinase activity
GO:0009411 IEA response to UV
GO:0009650 IGI UV protection
GO:0016887 IEA ATPase activity
GO:0032564 IEA dATP binding
GO:0033683 IEA nucleotide-excision repair, DNA incision
GO:0035315 IEA hair cell differentiation
GO:0042277 IEA peptide binding
GO:0043065 IEA positive regulation of apoptotic process
GO:0043138 ISS 3'-5' DNA helicase activity
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0047485 IEA protein N-terminus binding
GO:1901990 IEA regulation of mitotic cell cycle phase transition

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002402 ercc3 excision repair cross-complementing rodent repair deficiency, complementation group 3 protein_coding Danio_rerio
ENSG00000163161 ERCC3 excision repair cross-complementation group 3 protein_coding Homo_sapiens

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