C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase C, iota
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000163558 PRKCI 9606 + 3:170222365-170305981 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000295797 PRKCI-001 170222365-170305981 protein_coding
  ENST00000476635 PRKCI-002 170291642-170305977 retained_intron
  ENST00000482353 PRKCI-005 170281610-170284596 retained_intron
  ENST00000483697 PRKCI-006 170293347-170297328 retained_intron
  ENST00000485837 PRKCI-007 170293332-170303165 retained_intron
  ENST00000488541 PRKCI-004 170280145-170281238 retained_intron
  ENST00000493761 PRKCI-003 170280240-170281537 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000295797ENST00000476635ENST00000483697
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000295797 2.549±0.00 1.595±0.00 1.172±0.00 5.195±0.85 3.750±1.68 3.974±0.91 1.983±0.65 3.871±2.75 2.064±1.42 5.425±0.49 1.511±1.02 5.888±1.32 2.717±0.64 6.850±0.08
ENST00000476635 0.672±0.00 0.468±0.00 N/A N/A 0.916±0.00 N/A 0.272±0.00 N/A 0.162±0.00 N/A N/A N/A N/A N/A
ENST00000483697 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.662±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002XN CIL_0002XN_0001 CGP 3:170086732-170305981
CIL_0002XK CIL_0002XK_0001 CGP 3:170222365-170396835

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 IEA Golgi membrane
GO:0004672 IDA:IEA protein kinase activity
GO:0004674 IDA:IEA protein serine/threonine kinase activity
GO:0004697 ISS protein kinase C activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 TAS:IEA ATP binding
GO:0005543 IDA phospholipid binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0005829 IDA cytosol
GO:0005886 TAS plasma membrane
GO:0005923 IEA tight junction
GO:0006468 IDA:IEA protein phosphorylation
GO:0006612 NAS protein targeting to membrane
GO:0007010 NAS cytoskeleton organization
GO:0007015 IEA actin filament organization
GO:0008270 IEA zinc ion binding
GO:0010976 IMP positive regulation of neuron projection development
GO:0015630 IDA microtubule cytoskeleton
GO:0016192 TAS vesicle-mediated transport
GO:0016324 IEA apical plasma membrane
GO:0016477 IEA cell migration
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019904 IEA protein domain specific binding
GO:0031252 IEA cell leading edge
GO:0032869 ISS cellular response to insulin stimulus
GO:0034329 TAS cell junction assembly
GO:0034351 IMP negative regulation of glial cell apoptotic process
GO:0034613 IEA cellular protein localization
GO:0035089 IEA establishment of apical/basal cell polarity
GO:0035556 IEA intracellular signal transduction
GO:0042462 IEA eye photoreceptor cell development
GO:0043066 TAS negative regulation of apoptotic process
GO:0043220 IEA Schmidt-Lanterman incisure
GO:0043234 IEA protein complex
GO:0043434 IEA response to peptide hormone
GO:0043524 IDA negative regulation of neuron apoptotic process
GO:0045171 IDA intercellular bridge
GO:0045177 IEA apical part of cell
GO:0045197 TAS establishment or maintenance of epithelial cell apical/basal polarity
GO:0045216 IMP cell-cell junction organization
GO:0046326 ISS positive regulation of glucose import
GO:0046903 NAS secretion
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048194 IEA Golgi vesicle budding
GO:0051092 IDA positive regulation of NF-kappaB transcription factor activity
GO:0060252 IMP positive regulation of glial cell proliferation
GO:0061024 NAS membrane organization
GO:0070062 IDA extracellular vesicular exosome
GO:0070555 IEA response to interleukin-1
GO:0070830 TAS tight junction assembly
GO:0090004 ISS positive regulation of establishment of protein localization to plasma membrane
GO:2000353 IMP positive regulation of endothelial cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021225 prkci protein kinase C, iota protein_coding Danio_rerio
ENSMUSG00000037643 Prkci protein kinase C, iota protein_coding Mus_musculus

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