C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase C, iota
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037643 Prkci 10090 + 3:30995747-31052741 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000108249 Prkci-001 30995747-31052741 protein_coding
  ENSMUST00000123971 Prkci-003 31031722-31039397 processed_transcript
  ENSMUST00000130238 Prkci-002 31005193-31034513 protein_coding
  ENSMUST00000130706 Prkci-004 31038515-31039969 retained_intron
  ENSMUST00000136086 Prkci-005 31038450-31041224 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000108249ENSMUST00000136086
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000108249 12.595±2.01 4.557±0.86 32.160±5.81 11.031±2.70 9.730±1.08 14.838±6.11 3.026±0.35 8.307±0.52 4.045±1.39 25.402±4.68 0.768±0.26 6.958±2.50 15.830±8.00 3.595±1.60
ENSMUST00000136086 N/A N/A N/A 68.039±0.00 N/A N/A N/A N/A N/A N/A N/A 99.983±0.00 190.051±1.21 20.699±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002XN CIL_0002XN_0002 CGP 3:30899295-31052741
CIL_0002XK CIL_0002XK_0002 CGP 3:30995747-31122577

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 IEA Golgi membrane
GO:0004672 ISS protein kinase activity
GO:0004674 ISS protein serine/threonine kinase activity
GO:0004697 IDA protein kinase C activity
GO:0005524 IEA ATP binding
GO:0005543 ISS phospholipid binding
GO:0005634 IDA:ISS nucleus
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0005829 ISS cytosol
GO:0005886 IEA plasma membrane
GO:0005923 IEA tight junction
GO:0006468 IDA protein phosphorylation
GO:0007015 IMP actin filament organization
GO:0008270 IEA zinc ion binding
GO:0010976 ISS positive regulation of neuron projection development
GO:0015630 IEA microtubule cytoskeleton
GO:0016324 IDA apical plasma membrane
GO:0016477 IEA cell migration
GO:0019904 IEA protein domain specific binding
GO:0031252 IEA cell leading edge
GO:0032869 IMP cellular response to insulin stimulus
GO:0034351 ISS negative regulation of glial cell apoptotic process
GO:0034613 IEA cellular protein localization
GO:0035089 IMP establishment of apical/basal cell polarity
GO:0035556 IEA intracellular signal transduction
GO:0042462 IMP eye photoreceptor cell development
GO:0043220 IDA Schmidt-Lanterman incisure
GO:0043234 IEA protein complex
GO:0043434 IEA response to peptide hormone
GO:0043524 ISS negative regulation of neuron apoptotic process
GO:0045171 IEA intercellular bridge
GO:0045177 IDA apical part of cell
GO:0045216 ISS cell-cell junction organization
GO:0046326 IMP positive regulation of glucose import
GO:0048194 IEA Golgi vesicle budding
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0060252 ISS positive regulation of glial cell proliferation
GO:0070062 IEA extracellular vesicular exosome
GO:0070555 IEA response to interleukin-1
GO:0090004 IMP positive regulation of establishment of protein localization to plasma membrane
GO:2000353 ISS positive regulation of endothelial cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021225 prkci protein kinase C, iota protein_coding Danio_rerio
ENSG00000163558 PRKCI protein kinase C, iota protein_coding Homo_sapiens

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