C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TCDD-inducible poly(ADP-ribose) polymerase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000163659 TIPARP 9606 + 3:156673235-156706770 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000295924 TIPARP-001 156674342-156706770 protein_coding
  ENST00000461166 TIPARP-003 156674845-156706750 protein_coding
  ENST00000473702 TIPARP-004 156675569-156703695 protein_coding
  ENST00000481853 TIPARP-005 156676664-156705120 protein_coding
  ENST00000486483 TIPARP-002 156673235-156705139 protein_coding
  ENST00000495891 TIPARP-006 156681166-156706750 protein_coding
  ENST00000542783 TIPARP-201 156676664-156706766 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000295924ENST00000461166ENST00000473702ENST00000481853ENST00000495891ENST00000542783
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000295924 2.506±0.00 1.371±0.00 1.815±0.00 4.232±2.57 3.797±0.01 2.969±0.44 5.291±4.08 1.634±0.71 3.249±1.54 7.426±1.94 1.395±0.10 7.218±5.18 1.498±0.30 12.869±2.17
ENST00000461166 N/A N/A N/A N/A N/A N/A 0.428±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000473702 N/A N/A N/A N/A N/A N/A N/A 1.261±0.00 N/A N/A 1.770±0.12 N/A N/A N/A
ENST00000481853 N/A N/A 1.906±0.00 2.583±0.00 7.465±0.00 3.156±0.00 3.734±1.14 N/A 8.115±0.00 N/A N/A 9.306±4.20 3.192±0.00 25.197±16.13
ENST00000495891 0.789±0.00 0.705±0.00 N/A 5.966±0.00 2.187±0.00 2.424±0.00 6.222±0.00 2.961±0.00 1.156±0.00 2.969±0.00 N/A 4.502±0.00 1.002±0.00 9.309±0.00
ENST00000542783 1.160±0.00 1.510±0.00 N/A N/A N/A N/A N/A 2.728±0.00 N/A N/A 1.627±0.00 8.311±0.00 0.406±0.21 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000668 CIL_000668_0002 CGP 3:156540140-156706770
CIL_00066E CIL_00066E_0001 CGP 3:156673235-157046129

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001570 IEA vasculogenesis
GO:0001822 IEA kidney development
GO:0003950 IDA:IEA NAD+ ADP-ribosyltransferase activity
GO:0005634 IDA nucleus
GO:0006471 IEA protein ADP-ribosylation
GO:0006807 IEA nitrogen compound metabolic process
GO:0008209 IEA androgen metabolic process
GO:0008210 IEA estrogen metabolic process
GO:0008585 IEA female gonad development
GO:0009791 IEA post-embryonic development
GO:0010629 IMP negative regulation of gene expression
GO:0030097 IEA hemopoiesis
GO:0035326 IDA enhancer binding
GO:0044236 IEA multicellular organismal metabolic process
GO:0045732 IMP positive regulation of protein catabolic process
GO:0046872 IEA metal ion binding
GO:0048008 IEA platelet-derived growth factor receptor signaling pathway
GO:0048705 IEA skeletal system morphogenesis
GO:0048745 IEA smooth muscle tissue development
GO:0060021 IEA palate development
GO:0060325 IEA face morphogenesis
GO:0071407 IDA cellular response to organic cyclic compound

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061841 tiparp TCDD-inducible poly(ADP-ribose) polymerase protein_coding Danio_rerio
ENSMUSG00000034640 Tiparp TCDD-inducible poly(ADP-ribose) polymerase protein_coding Mus_musculus

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