C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, ionotropic, kainate 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000163873 GRIK3 9606 - 1:36795527-37034129 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000373091 GRIK3-001 36795527-37034125 protein_coding
  ENST00000373093 GRIK3-002 36804618-37034129 protein_coding
  ENST00000462621 GRIK3-003 36849674-36859136 processed_transcript
  ENST00000479620 GRIK3-004 36849948-36853687 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000373091ENST00000373093
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000373091 0.097±0.00 0.435±0.00 0.012±0.00 3.011±0.36 0.195±0.04 1.038±0.86 0.167±0.09 0.018±0.00 0.223±0.22 0.024±0.01 N/A 0.081±0.10 0.008±0.00 0.538±0.18
ENST00000373093 0.186±0.00 N/A N/A N/A N/A 0.297±0.00 0.124±0.00 N/A N/A N/A 0.029±0.00 0.043±0.00 0.012±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001640 IDA adenylate cyclase inhibiting G-protein coupled glutamate receptor activity
GO:0004970 ISS:IEA ionotropic glutamate receptor activity
GO:0005234 IBA:IEA extracellular-glutamate-gated ion channel activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0007196 IDA adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
GO:0007215 IDA glutamate receptor signaling pathway
GO:0007216 IDA G-protein coupled glutamate receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0008066 TAS glutamate receptor activity
GO:0015277 IDA kainate selective glutamate receptor activity
GO:0016020 IEA membrane
GO:0030054 IEA cell junction
GO:0030424 ISS axon
GO:0030425 ISS dendrite
GO:0032839 ISS dendrite cytoplasm
GO:0032983 IBA kainate selective glutamate receptor complex
GO:0034220 IEA ion transmembrane transport
GO:0035235 IEA ionotropic glutamate receptor signaling pathway
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0042391 ISS regulation of membrane potential
GO:0042734 IBA presynaptic membrane
GO:0043195 ISS terminal bouton
GO:0043204 ISS perikaryon
GO:0045211 IBA postsynaptic membrane
GO:0051967 ISS negative regulation of synaptic transmission, glutamatergic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077715 GRIK3 glutamate receptor, ionotropic, kainate 3 protein_coding Danio_rerio
ENSMUSG00000001985 Grik3 glutamate receptor, ionotropic, kainate 3 protein_coding Mus_musculus

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