C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ring finger protein 168, E3 ubiquitin protein ligase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000163961 RNF168 9606 - 3:196468783-196503768 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000318037 RNF168-001 196468783-196503768 protein_coding
  ENST00000437070 RNF168-002 196471760-196503677 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000318037ENST00000437070
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000318037 8.614±0.00 4.289±0.00 0.672±0.00 2.684±1.01 1.604±0.23 3.379±1.27 1.591±0.72 2.596±0.36 1.941±0.49 3.694±1.82 1.314±0.58 3.741±1.02 1.987±1.76 8.729±1.33
ENST00000437070 N/A N/A 1.404±0.00 0.669±0.00 3.360±0.00 1.461±0.00 0.975±0.14 N/A 1.393±0.00 0.908±0.00 0.601±0.30 N/A N/A 5.313±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000151 IDA ubiquitin ligase complex
GO:0003682 IDA chromatin binding
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005739 IDA mitochondrion
GO:0006302 IDA double-strand break repair
GO:0006511 IDA ubiquitin-dependent protein catabolic process
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0008270 IEA zinc ion binding
GO:0010212 IDA response to ionizing radiation
GO:0016567 IDA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0031491 IDA nucleosome binding
GO:0034244 IMP negative regulation of transcription elongation from RNA polymerase II promoter
GO:0035518 IDA histone H2A monoubiquitination
GO:0035861 IDA site of double-strand break
GO:0036297 TAS interstrand cross-link repair
GO:0036351 IDA histone H2A-K13 ubiquitination
GO:0036352 IDA histone H2A-K15 ubiquitination
GO:0042393 IDA histone binding
GO:0043130 IDA ubiquitin binding
GO:0045190 ISS isotype switching
GO:0045739 IDA positive regulation of DNA repair
GO:0046872 IEA metal ion binding
GO:0070530 IDA K63-linked polyubiquitin binding
GO:0070534 IDA protein K63-linked ubiquitination
GO:0070535 IDA histone H2A K63-linked ubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026757 rnf168 ring finger protein 168 protein_coding Danio_rerio
ENSMUSG00000014074 Rnf168 ring finger protein 168 protein_coding Mus_musculus

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