C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ring finger protein 168
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000014074 Rnf168 10090 + 16:32277459-32301434 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000014218 Rnf168-001 32277461-32300906 protein_coding
  ENSMUST00000155649 Rnf168-002 32277459-32289194 protein_coding
  ENSMUST00000171474 Rnf168-201 32277461-32301434 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000014218ENSMUST00000155649ENSMUST00000171474
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000014218 1.982±0.28 1.053±0.30 3.181±1.41 3.024±0.89 1.454±0.28 1.878±0.22 1.758±0.52 1.694±0.48 2.486±1.10 1.920±0.61 1.850±0.24 2.019±1.48 3.319±1.26 3.758±0.55
ENSMUST00000155649 3.475±1.45 7.189±1.59 N/A 3.895±1.93 2.978±0.66 3.727±0.94 1.046±0.14 1.549±0.61 1.352±0.55 4.025±1.81 1.611±0.00 5.841±2.61 7.215±0.00 10.376±11.32
ENSMUST00000171474 0.865±0.45 0.738±0.22 1.625±0.32 1.899±0.66 0.470±0.13 0.701±0.24 0.392±0.19 0.533±0.22 1.897±1.36 0.719±0.03 0.706±0.17 1.993±0.60 1.290±0.72 1.042±0.06

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008QR CIL_0008QR_0002 VISTA 16:32268412-32870796

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000151 ISS ubiquitin ligase complex
GO:0003682 ISS chromatin binding
GO:0004842 ISS ubiquitin-protein transferase activity
GO:0005634 ISS nucleus
GO:0005739 IEA mitochondrion
GO:0006302 ISS double-strand break repair
GO:0006511 ISS ubiquitin-dependent protein catabolic process
GO:0006974 ISS cellular response to DNA damage stimulus
GO:0008270 IEA zinc ion binding
GO:0010212 ISS response to ionizing radiation
GO:0016567 ISS protein ubiquitination
GO:0016874 IEA ligase activity
GO:0031491 IEA nucleosome binding
GO:0034244 ISS negative regulation of transcription elongation from RNA polymerase II promoter
GO:0035518 ISS histone H2A monoubiquitination
GO:0035861 ISS site of double-strand break
GO:0036351 ISS histone H2A-K13 ubiquitination
GO:0036352 ISS histone H2A-K15 ubiquitination
GO:0042393 ISS histone binding
GO:0043130 ISS ubiquitin binding
GO:0045190 IMP isotype switching
GO:0045739 ISS positive regulation of DNA repair
GO:0070530 ISS K63-linked polyubiquitin binding
GO:0070534 ISS protein K63-linked ubiquitination
GO:0070535 ISS histone H2A K63-linked ubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026757 rnf168 ring finger protein 168 protein_coding Danio_rerio
ENSG00000163961 RNF168 ring finger protein 168, E3 ubiquitin protein ligase protein_coding Homo_sapiens

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