C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: guanylate cyclase 1, soluble, alpha 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000164116 GUCY1A3 9606 + 4:155666711-155732349 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000296518 GUCY1A3-010 155667198-155732349 protein_coding
  ENST00000393832 GUCY1A3-009 155667129-155732345 protein_coding
  ENST00000443668 GUCY1A3-008 155667104-155732347 nonsense_mediated_decay
  ENST00000455639 GUCY1A3-006 155666963-155730416 protein_coding
  ENST00000506455 GUCY1A3-002 155666711-155730432 protein_coding
  ENST00000509901 GUCY1A3-007 155667042-155730445 nonsense_mediated_decay
  ENST00000511108 GUCY1A3-001 155666726-155730630 protein_coding
  ENST00000511507 GUCY1A3-005 155666848-155722569 protein_coding
  ENST00000512983 GUCY1A3-003 155666828-155711381 retained_intron
  ENST00000513574 GUCY1A3-013 155667663-155730432 protein_coding
  ENST00000515201 GUCY1A3-011 155667338-155730442 nonsense_mediated_decay
  ENST00000515602 GUCY1A3-021 155666936-155710611 processed_transcript
  ENST00000621234 GUCY1A3-201 155666726-155730622 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000296518ENST00000393832ENST00000443668ENST00000455639ENST00000506455ENST00000511108ENST00000511507ENST00000513574
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000296518 N/A N/A 2.729±0.00 N/A 2.763±0.00 1.954±0.00 N/A N/A N/A 0.572±0.00 2.198±0.36 N/A
ENST00000393832 N/A N/A 1.167±0.00 4.900±0.00 N/A 0.235±0.00 0.278±0.00 N/A 0.387±0.00 0.773±0.03 5.521±0.00 0.332±0.00
ENST00000443668 N/A N/A N/A N/A N/A N/A 0.071±0.00 N/A 0.374±0.04 N/A N/A N/A
ENST00000455639 N/A 2.862±0.00 3.012±0.00 N/A 1.552±0.00 N/A N/A N/A N/A N/A 1.660±0.00 N/A
ENST00000506455 N/A N/A N/A 4.164±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000511108 N/A N/A N/A N/A N/A 0.892±0.00 0.241±0.00 N/A 0.446±0.00 0.532±0.00 N/A N/A
ENST00000511507 3.672±0.00 N/A 5.401±0.00 N/A N/A N/A N/A N/A 0.619±0.00 1.715±0.00 N/A N/A
ENST00000513574 N/A N/A N/A N/A N/A 0.886±0.00 0.249±0.00 2.474±0.00 N/A 1.788±0.00 5.890±0.00 0.560±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000O9 CIL_0000O9_0002 CGP 4:155342658-155732349
CIL_0000OA CIL_0000OA_0002 CGP 4:155666711-155807591

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0004383 IEA guanylate cyclase activity
GO:0004872 TAS receptor activity
GO:0005525 IEA GTP binding
GO:0006182 IEA cGMP biosynthetic process
GO:0007263 TAS nitric oxide mediated signal transduction
GO:0007596 TAS blood coagulation
GO:0008015 TAS blood circulation
GO:0008074 TAS guanylate cyclase complex, soluble
GO:0008217 IEA regulation of blood pressure
GO:0009190 IEA cyclic nucleotide biosynthetic process
GO:0016021 IEA integral component of membrane
GO:0016849 IEA phosphorus-oxygen lyase activity
GO:0020037 IEA heme binding
GO:0030828 IEA positive regulation of cGMP biosynthetic process
GO:0035556 IEA intracellular signal transduction
GO:0052565 IEA response to defense-related host nitric oxide production
GO:0060087 IEA relaxation of vascular smooth muscle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013787 gucy1a3 guanylate cyclase 1, soluble, alpha 3 protein_coding Danio_rerio
ENSMUSG00000033910 Gucy1a3 guanylate cyclase 1, soluble, alpha 3 protein_coding Mus_musculus

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