C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000164258 NDUFS4 9606 + 5:53560633-53683340 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000296684 NDUFS4-001 53560635-53683340 protein_coding
  ENST00000502423 NDUFS4-002 53560635-53683138 nonsense_mediated_decay
  ENST00000506765 NDUFS4-005 53560675-53683338 protein_coding
  ENST00000506974 NDUFS4-004 53560647-53683338 nonsense_mediated_decay
  ENST00000507026 NDUFS4-003 53560633-53683219 nonsense_mediated_decay
  ENST00000509443 NDUFS4-006 53646195-53658789 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000296684ENST00000502423ENST00000506974ENST00000507026
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000296684 18.798±0.00 19.908±0.00 7.473±0.00 36.443±15.65 26.579±8.65 25.483±5.19 32.935±15.48 35.414±0.76 20.951±3.53 22.354±5.02 35.892±5.91 34.454±23.81 22.587±6.94 15.262±9.44
ENST00000502423 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.712±0.00 3.403±0.69 4.566±0.00 4.161±0.00
ENST00000506974 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.985±0.00
ENST00000507026 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.674±0.00 4.779±0.00 7.245±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007PO CIL_0007PO_0001 UCNEbase 5:53486896-54215574

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001932 IMP regulation of protein phosphorylation
GO:0005739 IDA mitochondrion
GO:0005743 TAS mitochondrial inner membrane
GO:0005747 IMP mitochondrial respiratory chain complex I
GO:0006120 NAS mitochondrial electron transport, NADH to ubiquinone
GO:0007420 IMP brain development
GO:0008137 IMP NADH dehydrogenase (ubiquinone) activity
GO:0016651 IEA oxidoreductase activity, acting on NAD(P)H
GO:0019933 IMP cAMP-mediated signaling
GO:0022900 IEA electron transport chain
GO:0022904 TAS respiratory electron transport chain
GO:0032981 IMP mitochondrial respiratory chain complex I assembly
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045271 IEA respiratory chain complex I
GO:0045333 IMP cellular respiration
GO:0048146 IMP positive regulation of fibroblast proliferation
GO:0051591 IMP response to cAMP
GO:0072593 IMP reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052840 ndufs4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, (NADH-coenzyme Q reductase) protein_coding Danio_rerio
ENSMUSG00000021764 Ndufs4 NADH dehydrogenase (ubiquinone) Fe-S protein 4 protein_coding Mus_musculus

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