C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine peptidase inhibitor, Kazal type 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000164266 SPINK1 9606 - 5:147824568-147831786 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000296695 SPINK1-001 147824568-147831786 protein_coding
  ENST00000505722 SPINK1-003 147824572-147828130 retained_intron
  ENST00000510027 SPINK1-002 147827086-147831635 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000296695ENST00000505722ENST00000510027
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000296695 0.256±0.00 N/A 5.078±0.00 N/A 32.662±0.00 29.384±0.71 0.210±0.00 26.349±26.17 406.308±377.89 N/A 0.125±0.00 14.583±14.47 0.114±0.00 0.040±0.00
ENST00000505722 0.468±0.00 N/A N/A N/A N/A 14.462±0.00 N/A 8.421±8.13 539.912±0.00 1.996±1.94 N/A 10.627±0.00 N/A 0.122±0.00
ENST00000510027 N/A 0.161±0.00 N/A 0.025±0.00 0.081±0.00 N/A 0.026±0.00 N/A N/A 0.006±0.00 N/A N/A N/A 0.059±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001AG CIL_0001AG_0001 CGP 5:147585439-147831786
CIL_0001AM CIL_0001AM_0001 CGP 5:147824568-147882191

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004866 TAS endopeptidase inhibitor activity
GO:0004867 IEA serine-type endopeptidase inhibitor activity
GO:0005515 IPI:IEA protein binding
GO:0005615 IEA extracellular space
GO:0010466 IEA negative regulation of peptidase activity
GO:0010751 IEA negative regulation of nitric oxide mediated signal transduction
GO:0030414 IEA peptidase inhibitor activity
GO:0050732 IEA negative regulation of peptidyl-tyrosine phosphorylation
GO:0060046 IEA regulation of acrosome reaction
GO:0070062 IDA extracellular vesicular exosome
GO:0090281 IEA negative regulation of calcium ion import
GO:1900004 IEA negative regulation of serine-type endopeptidase activity
GO:2001256 IEA regulation of store-operated calcium entry

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000024503 Spink3 serine peptidase inhibitor, Kazal type 3 protein_coding Mus_musculus

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