C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine peptidase inhibitor, Kazal type 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024503 Spink3 10090 - 18:43728069-43737237 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025381 Spink3-201 43728069-43737237 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000025381
Transcript ID Adipose Adrenal Bladder Brain Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000025381 0.265±0.13 0.526±0.14 0.233±0.11 0.073±0.02 162.592±16.88 0.186±0.06 753.191±127.72 113.097±72.86 1.008±0.60 0.568±0.32 205.462±250.58 0.120±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001AG CIL_0001AG_0002 CGP 18:43531408-43737237
CIL_0001AM CIL_0001AM_0002 CGP 18:43728069-43767399

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004867 IDA serine-type endopeptidase inhibitor activity
GO:0005615 IDA extracellular space
GO:0010466 IDA negative regulation of peptidase activity
GO:0010751 IDA negative regulation of nitric oxide mediated signal transduction
GO:0030414 IDA peptidase inhibitor activity
GO:0050732 IDA negative regulation of peptidyl-tyrosine phosphorylation
GO:0060046 IDA regulation of acrosome reaction
GO:0070062 IEA extracellular vesicular exosome
GO:0090281 IDA negative regulation of calcium ion import
GO:1900004 IMP negative regulation of serine-type endopeptidase activity
GO:2001256 IDA regulation of store-operated calcium entry

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000164266 SPINK1 serine peptidase inhibitor, Kazal type 1 protein_coding Homo_sapiens

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