C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 30 (zinc transporter), member 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000164756 SLC30A8 9606 + 8:116950273-117176714 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000427715 SLC30A8-201 116950951-117176714 protein_coding
  ENST00000456015 SLC30A8-002 117135328-117174091 protein_coding
  ENST00000518396 SLC30A8-007 117135027-117147138 protein_coding
  ENST00000518521 SLC30A8-006 117134808-117152975 protein_coding
  ENST00000519688 SLC30A8-001 117135259-117176714 protein_coding
  ENST00000520469 SLC30A8-008 117135074-117147609 retained_intron
  ENST00000521035 SLC30A8-009 116950949-117147011 processed_transcript
  ENST00000521243 SLC30A8-003 116950273-117172791 protein_coding
  ENST00000524274 SLC30A8-005 116950490-117153082 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000456015ENST00000518396ENST00000518521ENST00000519688ENST00000521035ENST00000521243ENST00000524274
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000456015 N/A N/A N/A N/A N/A 0.022±0.00 0.030±0.00 N/A 0.040±0.00 0.112±0.00 N/A 0.084±0.01 0.468±0.21
ENST00000518396 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.241±0.00 N/A
ENST00000518521 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.509±0.00 N/A N/A N/A
ENST00000519688 0.010±0.00 0.008±0.00 0.917±0.00 0.013±0.00 0.021±0.00 0.048±0.00 0.015±0.00 N/A 0.003±0.00 0.010±0.00 0.011±0.00 0.039±0.02 0.275±0.00
ENST00000521035 N/A 0.029±0.00 N/A 0.060±0.00 0.037±0.00 N/A N/A 0.029±0.00 N/A N/A 0.047±0.00 N/A N/A
ENST00000521243 N/A N/A 1.020±0.00 0.027±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.903±0.00
ENST00000524274 N/A N/A N/A 0.052±0.00 N/A N/A N/A N/A N/A N/A 0.059±0.00 0.109±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ZT CIL_0007ZT_0001 VISTA 8:116872414-117472859
CIL_0005RU CIL_0005RU_0001 CGP 8:116938199-117176714

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005385 IDA zinc ion transmembrane transporter activity
GO:0005886 IDA plasma membrane
GO:0006812 IEA cation transport
GO:0006829 IDA zinc ion transport
GO:0006882 ISS cellular zinc ion homeostasis
GO:0008270 IC zinc ion binding
GO:0008324 IEA cation transmembrane transporter activity
GO:0009749 IMP response to glucose
GO:0016021 IEA integral component of membrane
GO:0016023 ISS cytoplasmic membrane-bounded vesicle
GO:0030073 IMP insulin secretion
GO:0030141 IDA secretory granule
GO:0030667 TAS secretory granule membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0032024 ISS positive regulation of insulin secretion
GO:0032119 IDA sequestering of zinc ion
GO:0034341 IEA response to interferon-gamma
GO:0042803 ISS protein homodimerization activity
GO:0055085 TAS:IEA transmembrane transport
GO:0060627 ISS regulation of vesicle-mediated transport
GO:0061088 ISS regulation of sequestering of zinc ion
GO:0070555 IEA response to interleukin-1
GO:0071577 IDA zinc ion transmembrane transport
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057629 slc30a8 solute carrier family 30 (zinc transporter), member 8 protein_coding Danio_rerio
ENSMUSG00000022315 Slc30a8 solute carrier family 30 (zinc transporter), member 8 protein_coding Mus_musculus

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