C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: frizzled class receptor 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000164930 FZD6 9606 + 8:103298433-103332866 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000358755 FZD6-201 103298831-103332859 protein_coding
  ENST00000519011 FZD6-003 103298876-103331892 nonsense_mediated_decay
  ENST00000521195 FZD6-005 103299954-103331786 nonsense_mediated_decay
  ENST00000522484 FZD6-004 103298831-103332866 nonsense_mediated_decay
  ENST00000522566 FZD6-001 103298433-103332817 protein_coding
  ENST00000523739 FZD6-002 103298865-103331994 protein_coding
  ENST00000523933 FZD6-006 103298865-103329971 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000358755ENST00000519011ENST00000521195ENST00000522484ENST00000522566ENST00000523739ENST00000523933
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000358755 4.001±0.00 1.311±0.00 N/A 1.035±0.00 1.749±0.83 1.732±1.14 1.326±0.32 4.421±0.00 2.195±1.62 5.512±0.00 N/A 1.562±1.27 2.801±1.39 1.643±0.00
ENST00000519011 3.450±0.00 N/A N/A 1.483±0.00 0.995±0.00 N/A N/A N/A N/A 2.174±0.00 N/A 1.631±1.31 2.145±1.05 1.844±0.12
ENST00000521195 N/A N/A N/A N/A 1.179±0.00 2.228±0.00 0.759±0.00 N/A 2.719±0.00 1.611±0.00 0.594±0.20 N/A N/A N/A
ENST00000522484 1.258±0.00 N/A N/A N/A 0.902±0.00 N/A N/A N/A N/A N/A N/A 0.704±0.00 0.832±0.00 N/A
ENST00000522566 N/A 0.969±0.00 1.959±0.00 0.817±0.00 N/A N/A 0.372±0.00 N/A N/A 4.312±0.00 N/A N/A N/A 1.112±0.00
ENST00000523739 N/A N/A 0.784±0.00 N/A N/A N/A 0.409±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000523933 N/A N/A N/A N/A N/A N/A 0.615±0.00 0.502±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006A9 CIL_0006A9_0001 CGP 8:103140710-103332866
CIL_00060D CIL_00060D_0001 CGP 8:103298433-103382997

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IBA angiogenesis
GO:0001736 IBA establishment of planar polarity
GO:0001843 IBA neural tube closure
GO:0001942 IEA hair follicle development
GO:0004888 IEA transmembrane signaling receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005737 IBA cytoplasm
GO:0005886 TAS plasma membrane
GO:0005887 ISS integral component of plasma membrane
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007199 IBA G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
GO:0007275 IEA multicellular organismal development
GO:0007409 IBA axonogenesis
GO:0008406 IBA gonad development
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016055 IEA Wnt signaling pathway
GO:0016327 IBA apicolateral plasma membrane
GO:0017147 IBA Wnt-protein binding
GO:0030165 IBA PDZ domain binding
GO:0030168 IEA platelet activation
GO:0030901 IEA midbrain development
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032589 IBA neuron projection membrane
GO:0033278 IBA cell proliferation in midbrain
GO:0035567 IDA non-canonical Wnt signaling pathway
GO:0035880 IEA embryonic nail plate morphogenesis
GO:0042472 IBA inner ear morphogenesis
GO:0042813 IDA Wnt-activated receptor activity
GO:0043433 IDA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045177 IBA apical part of cell
GO:0060071 IEA Wnt signaling pathway, planar cell polarity pathway
GO:0090090 IMP negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042731 fzd6 frizzled homolog 6 (Drosophila) protein_coding Danio_rerio
ENSMUSG00000022297 Fzd6 frizzled homolog 6 (Drosophila) protein_coding Mus_musculus

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