C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fructose-1,6-bisphosphatase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000165140 FBP1 9606 - 9:94603133-94640249 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000375326 FBP1-001 94603133-94639507 protein_coding
  ENST00000414122 FBP1-002 94606815-94640137 protein_coding
  ENST00000415431 FBP1-201 94603141-94640249 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000375326ENST00000414122ENST00000415431
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000375326 6.470±0.00 3.481±0.00 10.385±0.00 0.859±0.80 5.518±5.06 1.375±0.01 0.636±0.00 36.421±5.79 157.927±156.41 28.519±17.32 0.189±0.07 4.166±2.25 3.910±1.27 1.477±0.69
ENST00000414122 N/A N/A N/A N/A 0.942±0.00 0.969±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000415431 N/A N/A N/A N/A N/A 0.248±0.00 0.262±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000664 CIL_000664_0001 CGP 9:94558720-94640249
CIL_0002J6 CIL_0002J6_0001 CGP 9:94603133-95087218

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005829 ISS cytosol
GO:0005975 IEA:TAS carbohydrate metabolic process
GO:0006000 TAS fructose metabolic process
GO:0006002 IDA fructose 6-phosphate metabolic process
GO:0006006 TAS glucose metabolic process
GO:0006094 ISS gluconeogenesis
GO:0006111 IMP regulation of gluconeogenesis
GO:0016208 IDA AMP binding
GO:0016311 IEA:IDA dephosphorylation
GO:0030308 IDA negative regulation of cell growth
GO:0035690 IDA cellular response to drug
GO:0042132 IEA:IDA fructose 1,6-bisphosphate 1-phosphatase activity
GO:0042578 IEA phosphoric ester hydrolase activity
GO:0042802 IPI identical protein binding
GO:0044281 TAS small molecule metabolic process
GO:0045820 IDA negative regulation of glycolytic process
GO:0046580 IDA negative regulation of Ras protein signal transduction
GO:0046854 IEA phosphatidylinositol phosphorylation
GO:0046872 IMP metal ion binding
GO:0048029 ISS monosaccharide binding
GO:0051289 IDA protein homotetramerization
GO:0070062 IDA extracellular vesicular exosome
GO:0071286 IDA cellular response to magnesium ion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000069805 Fbp1 fructose bisphosphatase 1 protein_coding Mus_musculus

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