C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000165953 SERPINA12 9606 - 14:94487274-94517844 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000341228 SERPINA12-001 94487283-94517844 protein_coding
  ENST00000556881 SERPINA12-002 94487274-94504222 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeLiverLungOvaryPlacentaTestisENST00000341228ENST00000556881
Transcript ID Adipose Liver Lung Ovary Placenta Testis
ENST00000341228 N/A N/A 0.064±0.00 0.032±0.00 N/A N/A
ENST00000556881 0.358±0.00 0.009±0.00 N/A 0.046±0.00 0.056±0.01 0.025±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000598 CIL_000598_0009 CGP 14:94462717-94517844
CIL_000598 CIL_000598_0008 CGP 14:94487274-94569913

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005515 IEA protein binding
GO:0005615 IEA extracellular space
GO:0005886 IEA plasma membrane
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0014068 IEA positive regulation of phosphatidylinositol 3-kinase signaling
GO:0030162 IBA regulation of proteolysis
GO:0045721 IEA negative regulation of gluconeogenesis
GO:0046628 IEA positive regulation of insulin receptor signaling pathway
GO:0051055 IEA negative regulation of lipid biosynthetic process
GO:0090181 IEA regulation of cholesterol metabolic process
GO:0090207 IEA regulation of triglyceride metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074712 si:ch211-186e20.2 si:ch211-186e20.2 protein_coding Danio_rerio
ENSDARG00000077960 si:ch211-186e20.7 si:ch211-186e20.7 protein_coding Danio_rerio
ENSDARG00000087143 serpina7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 protein_coding Danio_rerio
ENSDARG00000090286 serpina1 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 protein_coding Danio_rerio
ENSDARG00000090850 serpina1l serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like protein_coding Danio_rerio
ENSDARG00000090916 CR559930.2 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000091136 zgc:174259 zgc:174259 protein_coding Danio_rerio
ENSDARG00000091800 zgc:174260 zgc:174260 protein_coding Danio_rerio
ENSMUSG00000041567 Serpina12 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 protein_coding Mus_musculus

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