C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041567 Serpina12 10090 - 12:104028769-104044443 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000043915 Serpina12-001 104028769-104044443 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000043915
Transcript ID Adipose Adrenal Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000043915 0.033±0.02 0.023±0.01 0.006±0.00 0.253±0.20 0.017±0.01 0.012±0.00 0.068±0.07 0.055±0.02 0.053±0.05 0.073±0.04 0.121±0.14 0.006±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000598 CIL_000598_000L CGP 12:103994743-104044443
CIL_000598 CIL_000598_000J CGP 12:104028769-104106137

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005886 IDA plasma membrane
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0014068 IMP positive regulation of phosphatidylinositol 3-kinase signaling
GO:0030162 IBA regulation of proteolysis
GO:0045721 IDA negative regulation of gluconeogenesis
GO:0046628 IMP positive regulation of insulin receptor signaling pathway
GO:0051055 IDA negative regulation of lipid biosynthetic process
GO:0090181 IMP regulation of cholesterol metabolic process
GO:0090207 IMP regulation of triglyceride metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074712 si:ch211-186e20.2 si:ch211-186e20.2 protein_coding Danio_rerio
ENSDARG00000077960 si:ch211-186e20.7 si:ch211-186e20.7 protein_coding Danio_rerio
ENSDARG00000087143 serpina7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 protein_coding Danio_rerio
ENSDARG00000090286 serpina1 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 protein_coding Danio_rerio
ENSDARG00000090850 serpina1l serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like protein_coding Danio_rerio
ENSDARG00000090916 CR559930.2 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000091136 zgc:174259 zgc:174259 protein_coding Danio_rerio
ENSDARG00000091800 zgc:174260 zgc:174260 protein_coding Danio_rerio
ENSG00000165953 SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 protein_coding Homo_sapiens

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