C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine peptidase inhibitor, Kunitz type 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166145 SPINT1 9606 + 15:40844018-40858207 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000344051 SPINT1-001 40844018-40858207 protein_coding
  ENST00000562057 SPINT1-003 40844018-40857655 protein_coding
  ENST00000563135 SPINT1-011 40854210-40857123 retained_intron
  ENST00000563656 SPINT1-006 40844177-40853873 protein_coding
  ENST00000564375 SPINT1-008 40853510-40856967 protein_coding
  ENST00000566642 SPINT1-010 40854378-40856021 retained_intron
  ENST00000566928 SPINT1-007 40853196-40856826 protein_coding
  ENST00000568200 SPINT1-012 40855801-40856899 retained_intron
  ENST00000568580 SPINT1-005 40844675-40856949 protein_coding
  ENST00000568823 SPINT1-013 40844067-40853783 protein_coding
  ENST00000569589 SPINT1-009 40853816-40856969 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000344051ENST00000562057ENST00000563135ENST00000563656ENST00000564375ENST00000566928ENST00000568580ENST00000568823
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000344051 N/A N/A 0.548±0.00 N/A N/A 1.712±0.00 N/A 0.407±0.00 N/A N/A N/A 1.769±0.00 36.138±0.00 N/A
ENST00000562057 0.945±0.00 3.571±0.00 0.921±0.00 0.151±0.00 8.512±6.36 5.331±2.02 0.215±0.00 47.879±0.00 0.924±0.11 8.241±6.68 N/A 22.861±23.98 225.184±9.15 7.914±0.00
ENST00000563135 N/A N/A N/A 0.153±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000563656 N/A N/A N/A 0.120±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.255±0.00
ENST00000564375 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.311±0.00 N/A N/A N/A N/A
ENST00000566928 N/A N/A N/A N/A N/A N/A 0.205±0.04 N/A N/A N/A N/A N/A N/A N/A
ENST00000568580 N/A N/A 1.205±0.00 N/A 3.910±0.00 4.369±0.00 N/A N/A 2.517±0.00 1.341±0.00 N/A 4.191±0.00 N/A N/A
ENST00000568823 N/A N/A N/A 0.064±0.00 N/A N/A 0.149±0.00 N/A N/A N/A 0.071±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000794 CIL_000794_0001 CGP 15:40815445-40858207
CIL_000797 CIL_000797_0001 CGP 15:40844018-40874289

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001892 IEA embryonic placenta development
GO:0004867 IEA serine-type endopeptidase inhibitor activity
GO:0005515 IEA protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0016020 TAS membrane
GO:0030198 IEA extracellular matrix organization
GO:0060670 IEA branching involved in labyrinthine layer morphogenesis
GO:0060674 IEA placenta blood vessel development
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012467 spint1b serine peptidase inhibitor, Kunitz type 1 b protein_coding Danio_rerio
ENSDARG00000023673 spint1a serine peptidase inhibitor, Kunitz type 1 a protein_coding Danio_rerio
ENSMUSG00000027315 Spint1 serine protease inhibitor, Kunitz type 1 protein_coding Mus_musculus

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