C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine protease inhibitor, Kunitz type 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027315 Spint1 10090 + 2:119237362-119249527 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028783 Spint1-001 119237362-119249514 protein_coding
  ENSMUST00000110816 Spint1-002 119237477-119249195 protein_coding
  ENSMUST00000110817 Spint1-003 119237553-119249527 protein_coding
  ENSMUST00000134872 Spint1-005 119248205-119249049 retained_intron
  ENSMUST00000139903 Spint1-004 119246373-119248902 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028783ENSMUST00000110816ENSMUST00000110817ENSMUST00000134872ENSMUST00000139903
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028783 5.177±3.65 0.388±0.25 43.024±3.85 0.312±0.06 5.277±3.03 47.255±7.85 0.315±0.00 23.964±4.53 0.139±0.06 14.035±1.80 0.079±0.02 6.075±1.69 17.042±10.45 0.936±0.45
ENSMUST00000110816 0.048±0.00 0.278±0.04 N/A N/A 2.269±0.00 13.724±1.92 0.057±0.01 N/A 0.109±0.01 4.429±0.90 N/A 2.799±1.62 23.929±8.13 1.543±0.00
ENSMUST00000110817 1.073±0.76 0.581±0.20 22.991±2.30 0.357±0.27 5.134±0.39 28.133±8.89 0.261±0.14 14.793±1.13 0.148±0.06 3.705±0.42 0.138±0.13 2.976±1.02 10.905±6.10 0.681±0.27
ENSMUST00000134872 N/A N/A N/A N/A N/A N/A 0.087±0.00 N/A 0.082±0.00 N/A 0.102±0.00 N/A N/A N/A
ENSMUST00000139903 N/A N/A N/A N/A N/A N/A 0.167±0.00 N/A N/A N/A 0.128±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000794 CIL_000794_0002 CGP 2:119218119-119249527
CIL_000797 CIL_000797_0002 CGP 2:119237362-119271272

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001892 IMP embryonic placenta development
GO:0004867 IEA serine-type endopeptidase inhibitor activity
GO:0005615 IEA extracellular space
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0030198 IMP extracellular matrix organization
GO:0060670 IMP branching involved in labyrinthine layer morphogenesis
GO:0060674 IMP placenta blood vessel development
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012467 spint1b serine peptidase inhibitor, Kunitz type 1 b protein_coding Danio_rerio
ENSDARG00000023673 spint1a serine peptidase inhibitor, Kunitz type 1 a protein_coding Danio_rerio
ENSG00000166145 SPINT1 serine peptidase inhibitor, Kunitz type 1 protein_coding Homo_sapiens

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