C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase 2, regulatory subunit B'', beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167393 PPP2R3B 9606 - X:333963-386955 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000381625 PPP2R3B-002 347611-374044 protein_coding
  ENST00000390665 PPP2R3B-001 333963-386710 protein_coding
  ENST00000445792 PPP2R3B-007 344896-386955 retained_intron
  ENST00000468169 PPP2R3B-006 338613-345629 retained_intron
  ENST00000475859 PPP2R3B-009 346720-347838 retained_intron
  ENST00000477110 PPP2R3B-003 334239-347324 retained_intron
  ENST00000477636 PPP2R3B-005 341911-346514 retained_intron
  ENST00000479438 PPP2R3B-008 334235-341711 retained_intron
  ENST00000484364 PPP2R3B-004 340765-345626 retained_intron
  ENST00000496630 PPP2R3B-010 346637-361516 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000381625ENST00000390665ENST00000445792ENST00000468169ENST00000477110ENST00000477636ENST00000479438ENST00000484364
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000381625 N/A N/A 0.129±0.00 N/A 0.670±0.00 N/A 5.416±0.00 N/A 2.172±0.00 N/A 21.376±4.16 N/A N/A N/A
ENST00000390665 0.811±0.00 1.968±0.00 N/A 1.104±0.22 1.859±1.59 0.819±0.08 0.630±0.00 1.049±0.00 0.718±0.00 0.994±0.80 10.960±0.00 3.490±2.06 5.362±1.55 8.867±0.83
ENST00000445792 N/A N/A N/A N/A 0.163±0.00 N/A N/A N/A N/A N/A N/A 0.351±0.00 N/A N/A
ENST00000468169 0.587±0.00 3.069±0.00 N/A 1.381±0.00 N/A 1.091±0.00 N/A 0.388±0.00 0.830±0.00 N/A 9.372±1.74 5.509±0.00 7.443±0.00 10.433±5.34
ENST00000477110 0.240±0.00 0.591±0.00 0.041±0.00 0.302±0.00 0.495±0.34 0.171±0.03 N/A N/A 0.102±0.01 0.208±0.04 N/A 0.666±0.39 N/A 0.811±0.00
ENST00000477636 N/A N/A N/A N/A N/A N/A N/A N/A 1.675±0.00 N/A N/A 9.336±0.00 N/A N/A
ENST00000479438 N/A 2.390±0.00 0.057±0.00 N/A N/A N/A N/A 1.957±0.00 0.638±0.00 N/A N/A 4.203±0.87 4.295±0.00 8.127±4.25
ENST00000484364 N/A N/A N/A 1.009±0.02 N/A N/A N/A N/A N/A 0.576±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00027Q CIL_00027Q_0002 CGP X:333963-659411

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000159 ISS protein phosphatase type 2A complex
GO:0000278 TAS mitotic cell cycle
GO:0004721 TAS phosphoprotein phosphatase activity
GO:0004722 ISS protein serine/threonine phosphatase activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005634 TAS nucleus
GO:0005654 TAS nucleoplasm
GO:0006470 ISS protein dephosphorylation
GO:0007050 TAS cell cycle arrest
GO:0008601 TAS protein phosphatase type 2A regulator activity
GO:0050790 TAS regulation of catalytic activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076004 ppp2r3b protein phosphatase 2, regulatory subunit B'', beta protein_coding Danio_rerio
ENSMUSG00000093803 Ppp2r3d protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta protein_coding Mus_musculus

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