C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: alkaline ceramidase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167769 ACER1 9606 - 19:6306142-6333629 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000301452 ACER1-001 6306142-6333629 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLungMuscleOvaryPlacentaTestisENST00000301452
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Lung Muscle Ovary Placenta Testis
ENST00000301452 0.100±0.00 0.135±0.00 0.107±0.00 0.098±0.00 0.132±0.00 0.070±0.00 0.110±0.00 0.028±0.00 0.013±0.00 0.120±0.06 0.045±0.00 0.605±0.19

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005GO CIL_0005GO_0002 CGP 19:6210379-6333629
CIL_0005OI CIL_0005OI_0001 CGP 19:6306142-6368908

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005783 IDA endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006665 ISS sphingolipid metabolic process
GO:0006672 IEA ceramide metabolic process
GO:0008544 IEP epidermis development
GO:0010446 IDA response to alkaline pH
GO:0016021 IEA integral component of membrane
GO:0016811 IEA hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0017040 IDA ceramidase activity
GO:0019216 IEA regulation of lipid metabolic process
GO:0030148 IDA sphingolipid biosynthetic process
GO:0030154 IMP cell differentiation
GO:0030216 IEP keratinocyte differentiation
GO:0044281 TAS small molecule metabolic process
GO:0046512 IDA sphingosine biosynthetic process
GO:0046514 ISS ceramide catabolic process
GO:0071277 IDA cellular response to calcium ion
GO:0071633 IDA dihydroceramidase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010347 acer1 alkaline ceramidase 1 protein_coding Danio_rerio
ENSMUSG00000045019 Acer1 alkaline ceramidase 1 protein_coding Mus_musculus

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