C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: alkaline ceramidase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000045019 Acer1 10090 - 17:56953490-56982126 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000056113 Acer1-201 56953490-56982126 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000056113
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000056113 0.028±0.00 0.368±0.11 0.090±0.01 0.068±0.03 0.950±0.76 40.364±7.53 0.014±0.00 0.017±0.00 0.027±0.01 1.485±1.32 0.062±0.01 0.093±0.04 0.055±0.01 0.023±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005GO CIL_0005GO_0003 CGP 17:56892612-56982126
CIL_0005OI CIL_0005OI_0002 CGP 17:56953490-56996371

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005783 IDA endoplasmic reticulum
GO:0006665 IDA sphingolipid metabolic process
GO:0008544 IEA epidermis development
GO:0010446 IEA response to alkaline pH
GO:0016021 IEA integral component of membrane
GO:0017040 IDA ceramidase activity
GO:0019216 IDA regulation of lipid metabolic process
GO:0030148 IEA sphingolipid biosynthetic process
GO:0030154 IEA cell differentiation
GO:0030216 IEA keratinocyte differentiation
GO:0046512 IEA sphingosine biosynthetic process
GO:0046514 IDA ceramide catabolic process
GO:0071277 IEA cellular response to calcium ion
GO:0071633 IEA dihydroceramidase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010347 acer1 alkaline ceramidase 1 protein_coding Danio_rerio
ENSG00000167769 ACER1 alkaline ceramidase 1 protein_coding Homo_sapiens

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