C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pyruvate dehydrogenase (lipoamide) beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168291 PDHB 9606 - 3:58427630-58433857 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000302746 PDHB-001 58427630-58433852 protein_coding
  ENST00000383714 PDHB-008 58427630-58433857 protein_coding
  ENST00000461692 PDHB-002 58427692-58433839 retained_intron
  ENST00000469364 PDHB-006 58427651-58433820 nonsense_mediated_decay
  ENST00000469827 PDHB-009 58431432-58433829 retained_intron
  ENST00000474765 PDHB-007 58427683-58433814 protein_coding
  ENST00000479945 PDHB-003 58427681-58433816 retained_intron
  ENST00000480626 PDHB-011 58430210-58433818 retained_intron
  ENST00000482894 PDHB-010 58431334-58433828 retained_intron
  ENST00000485460 PDHB-005 58427672-58433818 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000302746ENST00000383714ENST00000461692ENST00000469364ENST00000469827ENST00000482894ENST00000485460
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000302746 6.705±0.00 14.042±0.00 2.175±0.00 12.584±0.08 8.117±3.38 6.941±4.50 9.063±0.60 10.141±2.56 3.289±0.07 6.155±0.00 10.256±0.00 12.406±5.39 36.788±10.05 19.348±0.00
ENST00000383714 N/A N/A 1.924±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000461692 N/A N/A N/A N/A N/A N/A 31.946±0.00 13.248±0.00 12.937±0.00 4.638±0.00 10.376±0.00 9.851±1.19 15.474±0.00 21.889±0.00
ENST00000469364 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.664±0.00 N/A N/A N/A N/A
ENST00000469827 N/A N/A 20.536±0.00 59.028±0.00 13.134±0.00 17.926±0.00 44.250±0.00 25.895±0.00 11.626±0.00 15.293±0.00 34.614±0.00 17.858±0.00 N/A N/A
ENST00000482894 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 39.298±0.00 112.188±0.00 92.003±0.00
ENST00000485460 7.851±0.00 21.597±0.00 N/A 15.181±0.00 12.397±0.00 4.872±2.44 26.225±0.00 16.094±0.00 7.275±3.43 7.278±0.00 9.271±1.07 5.988±0.00 11.028±2.67 13.841±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002QD CIL_0002QD_0002 CGP 3:58332880-58433857
CIL_0002QQ CIL_0002QQ_0002 CGP 3:58427630-58502360

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004738 IDA pyruvate dehydrogenase activity
GO:0004739 IEA pyruvate dehydrogenase (acetyl-transferring) activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005739 IEA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0006006 IEA glucose metabolic process
GO:0006086 IDA acetyl-CoA biosynthetic process from pyruvate
GO:0006090 TAS pyruvate metabolic process
GO:0006099 IDA tricarboxylic acid cycle
GO:0008152 IEA metabolic process
GO:0010510 TAS regulation of acetyl-CoA biosynthetic process from pyruvate
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045254 IDA pyruvate dehydrogenase complex
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021346 pdhb pyruvate dehydrogenase (lipoamide) beta protein_coding Danio_rerio
ENSMUSG00000021748 Pdhb pyruvate dehydrogenase (lipoamide) beta protein_coding Mus_musculus

Loading