C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: PX domain containing serine/threonine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168297 PXK 9606 + 3:58332880-58426126 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000302779 PXK-201 58332880-58425151 protein_coding
  ENST00000356151 PXK-001 58332880-58425151 protein_coding
  ENST00000383715 PXK-010 58332903-58420728 protein_coding
  ENST00000383716 PXK-202 58332890-58426126 protein_coding
  ENST00000459676 PXK-012 58397138-58414527 protein_coding
  ENST00000463280 PXK-002 58332898-58426023 protein_coding
  ENST00000468776 PXK-008 58332885-58425058 nonsense_mediated_decay
  ENST00000477308 PXK-007 58332987-58425058 nonsense_mediated_decay
  ENST00000479134 PXK-009 58395674-58425874 protein_coding
  ENST00000479241 PXK-006 58332948-58426019 protein_coding
  ENST00000484288 PXK-004 58332911-58420960 protein_coding
  ENST00000491164 PXK-011 58333306-58382678 protein_coding
  ENST00000493474 PXK-003 58409616-58425175 protein_coding
  ENST00000495557 PXK-005 58408979-58420735 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000356151ENST00000383715ENST00000383716ENST00000459676ENST00000463280ENST00000468776ENST00000477308ENST00000479134ENST00000479241ENST00000484288
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000356151 1.815±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.766±0.00 1.776±0.00 N/A
ENST00000383715 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.102±0.00 N/A N/A N/A N/A
ENST00000383716 1.595±0.00 4.758±0.00 N/A 12.741±0.00 2.738±0.00 2.814±0.00 0.290±0.00 N/A N/A 1.658±0.00 N/A 4.217±0.00 1.459±0.00 1.174±0.00
ENST00000459676 N/A N/A 1.639±0.00 6.163±0.00 N/A 0.901±0.00 N/A N/A N/A 1.854±0.00 0.392±0.00 N/A N/A N/A
ENST00000463280 N/A N/A N/A N/A 1.047±0.00 N/A 0.574±0.21 1.893±0.00 N/A N/A N/A N/A N/A N/A
ENST00000468776 2.410±0.00 N/A 3.222±0.00 N/A 1.919±0.00 N/A N/A N/A N/A N/A N/A 0.809±0.00 4.288±0.00 2.462±0.00
ENST00000477308 N/A N/A 3.053±0.00 10.347±0.00 N/A N/A N/A 1.128±0.00 2.823±0.00 4.379±0.00 N/A 0.816±0.00 N/A 3.464±0.00
ENST00000479134 1.624±0.00 N/A 4.709±0.00 13.661±0.00 1.516±0.00 1.398±0.00 0.917±0.48 2.787±1.30 2.826±0.00 4.171±1.09 2.618±1.55 3.330±1.54 3.049±0.60 N/A
ENST00000479241 1.518±0.00 N/A N/A N/A 3.129±0.00 N/A 0.568±0.00 N/A N/A N/A N/A 2.361±1.03 N/A N/A
ENST00000484288 N/A N/A N/A N/A N/A 0.806±0.00 N/A N/A N/A N/A N/A 0.884±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002UI CIL_0002UI_0001 CGP 3:58306262-58426126
CIL_0002QD CIL_0002QD_0002 CGP 3:58332880-58433857

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 IEA actin binding
GO:0004672 IEA protein kinase activity
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005815 IDA microtubule organizing center
GO:0005886 IDA plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0006954 IMP inflammatory response
GO:0008022 ISS protein C-terminus binding
GO:0008152 IEA metabolic process
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0032780 ISS negative regulation of ATPase activity
GO:0035091 IEA phosphatidylinositol binding
GO:0043271 ISS negative regulation of ion transport
GO:0050804 ISS regulation of synaptic transmission

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063195 pxk PX domain containing serine/threonine kinase protein_coding Danio_rerio
ENSMUSG00000033885 Pxk PX domain containing serine/threonine kinase protein_coding Mus_musculus

Loading