C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: PX domain containing serine/threonine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000033885 Pxk 10090 + 14:8098213-8165111 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000036682 Pxk-201 8098213-8165111 protein_coding
  ENSMUST00000112689 Pxk-202 8098213-8165111 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000036682ENSMUST00000112689
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000036682 14.024±2.09 24.939±3.11 20.350±2.99 10.576±1.02 17.478±3.73 21.785±3.99 8.355±0.82 16.109±3.08 9.286±1.63 18.038±1.64 4.306±0.60 13.473±4.54 20.724±6.88 11.112±4.24
ENSMUST00000112689 N/A N/A N/A 6.784±3.35 N/A N/A N/A N/A N/A N/A N/A N/A 2.209±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002UI CIL_0002UI_0002 CGP 14:8090078-8165111
CIL_0002QD CIL_0002QD_0003 CGP 14:8098213-8172992

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 IEA actin binding
GO:0004672 IEA protein kinase activity
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0005815 IEA microtubule organizing center
GO:0005886 IDA plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0006954 IEA inflammatory response
GO:0008022 IPI protein C-terminus binding
GO:0032780 IDA negative regulation of ATPase activity
GO:0035091 IEA phosphatidylinositol binding
GO:0043271 IDA negative regulation of ion transport
GO:0050804 IEP regulation of synaptic transmission

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063195 pxk PX domain containing serine/threonine kinase protein_coding Danio_rerio
ENSG00000168297 PXK PX domain containing serine/threonine kinase protein_coding Homo_sapiens

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