C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: deoxythymidylate kinase (thymidylate kinase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168393 DTYMK 9606 - 2:241675742-241686991 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000305784 DTYMK-001 241675742-241686991 protein_coding
  ENST00000400770 DTYMK-002 241675747-241686944 nonsense_mediated_decay
  ENST00000420144 DTYMK-008 241676178-241685877 protein_coding
  ENST00000432348 DTYMK-004 241676123-241686742 nonsense_mediated_decay
  ENST00000445261 DTYMK-006 241676120-241686712 protein_coding
  ENST00000464603 DTYMK-003 241685116-241686781 retained_intron
  ENST00000493095 DTYMK-005 241682155-241686725 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000305784ENST00000400770ENST00000420144ENST00000432348ENST00000445261ENST00000464603ENST00000493095
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000305784 8.366±0.00 7.918±0.00 N/A 2.599±0.00 8.467±0.00 4.441±3.87 1.467±1.37 6.395±2.79 2.896±2.56 2.096±0.35 0.260±0.04 18.348±12.83 16.845±4.01 6.269±1.33
ENST00000400770 N/A 3.126±0.00 N/A 1.240±0.09 N/A 0.756±0.00 N/A N/A 0.894±0.61 N/A 0.329±0.00 3.991±0.00 N/A N/A
ENST00000420144 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 36.672±0.00 10.208±0.00 N/A
ENST00000432348 N/A 2.664±0.00 N/A 0.640±0.18 N/A N/A N/A N/A N/A N/A 0.244±0.13 N/A N/A N/A
ENST00000445261 N/A N/A 1.611±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 42.704±0.00 16.201±0.00 10.987±0.00
ENST00000464603 N/A N/A N/A 0.721±0.00 0.554±0.00 0.487±0.00 0.270±0.00 1.351±0.00 0.265±0.00 N/A 0.102±0.00 N/A N/A N/A
ENST00000493095 N/A N/A N/A N/A N/A N/A 0.599±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004UA CIL_0004UA_0002 CGP 2:241637213-241686991
CIL_0001U2 CIL_0001U2_0001 CGP 2:241675742-241729478

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004798 IDA:IEA thymidylate kinase activity
GO:0005524 IEA ATP binding
GO:0005739 IEA mitochondrion
GO:0005758 IEA mitochondrial intermembrane space
GO:0005759 IEA mitochondrial matrix
GO:0005829 TAS cytosol
GO:0006233 IEA dTDP biosynthetic process
GO:0006235 IEA dTTP biosynthetic process
GO:0007049 TAS cell cycle
GO:0008283 TAS cell proliferation
GO:0009165 IEA nucleotide biosynthetic process
GO:0015949 TAS nucleobase-containing small molecule interconversion
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0043627 IEA response to estrogen
GO:0044281 TAS small molecule metabolic process
GO:0045445 IEA myoblast differentiation
GO:0046686 IEA response to cadmium ion
GO:0046939 IEA nucleotide phosphorylation
GO:0046940 EXP nucleoside monophosphate phosphorylation
GO:0050145 EXP nucleoside phosphate kinase activity
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0071363 IEA cellular response to growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052103 dtymk deoxythymidylate kinase (thymidylate kinase) protein_coding Danio_rerio
ENSMUSG00000026281 Dtymk deoxythymidylate kinase protein_coding Mus_musculus

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