C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: farnesyltransferase, CAAX box, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168522 FNTA 9606 + 8:43034194-43085788 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000302279 FNTA-001 43056153-43085788 protein_coding
  ENST00000524546 FNTA-011 43056355-43070353 processed_transcript
  ENST00000525099 FNTA-003 43076647-43085780 retained_intron
  ENST00000525699 FNTA-009 43056592-43072307 protein_coding
  ENST00000526755 FNTA-002 43056308-43085788 nonsense_mediated_decay
  ENST00000527153 FNTA-010 43056328-43077272 processed_transcript
  ENST00000528400 FNTA-012 43084628-43085506 retained_intron
  ENST00000529687 FNTA-004 43056673-43085780 protein_coding
  ENST00000531266 FNTA-008 43056362-43077226 protein_coding
  ENST00000533336 FNTA-007 43058952-43084798 protein_coding
  ENST00000533368 FNTA-013 43056415-43077385 retained_intron
  ENST00000533383 FNTA-005 43056330-43085193 nonsense_mediated_decay
  ENST00000533559 FNTA-014 43034194-43069583 processed_transcript
  ENST00000533998 FNTA-006 43056331-43084757 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000302279ENST00000525099ENST00000526755ENST00000533368
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000302279 22.688±0.00 12.335±0.00 17.902±6.43 33.622±0.00 32.757±0.00 11.859±8.19 10.315±0.00 10.564±0.00 20.947±0.00 16.401±12.56 19.415±2.49 20.409±8.86 23.604±0.00
ENST00000525099 N/A N/A N/A N/A 1.314±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000526755 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.352±0.00
ENST00000533368 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 76.082±0.00 32.172±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004660 IDA protein farnesyltransferase activity
GO:0004661 IDA protein geranylgeranyltransferase activity
GO:0004662 IEA CAAX-protein geranylgeranyltransferase activity
GO:0004663 IEA Rab geranylgeranyltransferase activity
GO:0005515 IPI protein binding
GO:0005737 TAS cytoplasm
GO:0005829 TAS cytosol
GO:0005875 IDA microtubule associated complex
GO:0005953 IDA CAAX-protein geranylgeranyltransferase complex
GO:0005965 IDA protein farnesyltransferase complex
GO:0006915 TAS apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0007603 TAS phototransduction, visible light
GO:0008017 IDA microtubule binding
GO:0008318 IEA protein prenyltransferase activity
GO:0010469 IEA regulation of receptor activity
GO:0016056 TAS rhodopsin mediated signaling pathway
GO:0018342 IEA protein prenylation
GO:0018343 IDA protein farnesylation
GO:0018344 IDA protein geranylgeranylation
GO:0022400 TAS regulation of rhodopsin mediated signaling pathway
GO:0030548 IEA acetylcholine receptor regulator activity
GO:0030971 IEA receptor tyrosine kinase binding
GO:0043014 IDA alpha-tubulin binding
GO:0045213 IEA neurotransmitter receptor metabolic process
GO:0090044 IDA positive regulation of tubulin deacetylation
GO:0090045 IDA positive regulation of deacetylase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037665 fnta farnesyltransferase, CAAX box, alpha protein_coding Danio_rerio
ENSMUSG00000015994 Fnta farnesyltransferase, CAAX box, alpha protein_coding Mus_musculus

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