C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitochondrial fission factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168958 MFF 9606 + 2:227325151-227357836 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000304593 MFF-003 227325169-227357834 protein_coding
  ENST00000337110 MFF-002 227325268-227357833 protein_coding
  ENST00000349901 MFF-021 227325276-227357812 protein_coding
  ENST00000353339 MFF-001 227325239-227357833 protein_coding
  ENST00000354503 MFF-022 227325250-227357215 protein_coding
  ENST00000392059 MFF-201 227328678-227357836 protein_coding
  ENST00000409565 MFF-005 227325259-227357799 protein_coding
  ENST00000409616 MFF-008 227325262-227357151 protein_coding
  ENST00000418961 MFF-018 227325451-227330845 protein_coding
  ENST00000423098 MFF-010 227325151-227330763 protein_coding
  ENST00000436237 MFF-013 227325365-227330689 protein_coding
  ENST00000436791 MFF-014 227330701-227347383 processed_transcript
  ENST00000443428 MFF-016 227325443-227330801 protein_coding
  ENST00000452930 MFF-017 227325261-227340354 protein_coding
  ENST00000456345 MFF-019 227340292-227357381 protein_coding
  ENST00000460756 MFF-004 227325265-227357833 retained_intron
  ENST00000470090 MFF-009 227325271-227340561 retained_intron
  ENST00000476262 MFF-007 227351681-227357831 retained_intron
  ENST00000476924 MFF-020 227325221-227357254 processed_transcript
  ENST00000477362 MFF-015 227355298-227357181 retained_intron
  ENST00000489696 MFF-011 227325234-227332499 retained_intron
  ENST00000490857 MFF-006 227346725-227357833 retained_intron
  ENST00000524634 MFF-027 227325271-227357131 protein_coding
  ENST00000525195 MFF-025 227325271-227330822 protein_coding
  ENST00000530359 MFF-023 227325251-227347274 protein_coding
  ENST00000531278 MFF-024 227325257-227347379 protein_coding
  ENST00000534203 MFF-026 227325271-227355761 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000304593ENST00000349901ENST00000353339ENST00000354503ENST00000409565ENST00000409616ENST00000452930ENST00000460756ENST00000476924ENST00000490857ENST00000524634ENST00000530359
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000304593 4.457±0.00 7.053±0.00 10.667±0.00 2.166±0.00 11.633±0.00 1.847±0.00 21.256±0.00 5.021±0.00 6.488±0.00 N/A 9.970±6.25 7.763±0.37 20.643±0.00
ENST00000349901 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.584±0.00 N/A
ENST00000353339 N/A N/A N/A N/A N/A 0.928±0.00 N/A N/A N/A 6.273±0.60 4.685±0.00 N/A N/A
ENST00000354503 10.253±0.00 22.097±0.00 21.150±0.00 13.609±0.00 17.957±0.00 N/A N/A 6.360±3.85 10.880±0.00 10.624±0.00 13.828±7.21 12.292±1.45 30.698±0.00
ENST00000409565 N/A N/A N/A N/A N/A N/A N/A 2.568±0.00 N/A N/A N/A N/A N/A
ENST00000409616 N/A N/A N/A N/A N/A 2.504±0.00 N/A N/A N/A 10.651±0.00 N/A N/A 74.057±30.55
ENST00000452930 N/A N/A N/A N/A N/A N/A N/A 6.807±0.00 N/A N/A N/A N/A N/A
ENST00000460756 N/A N/A N/A 0.909±0.00 N/A N/A N/A N/A N/A N/A 1.201±0.00 N/A N/A
ENST00000476924 11.817±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000490857 N/A N/A N/A 2.066±0.00 5.042±0.00 N/A N/A N/A N/A N/A 2.436±0.00 N/A N/A
ENST00000524634 N/A N/A N/A N/A 11.959±0.00 N/A N/A N/A N/A N/A 36.273±0.00 28.872±0.00 132.867±0.00
ENST00000530359 N/A N/A N/A N/A N/A N/A N/A N/A N/A 22.906±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006XR CIL_0006XR_0001 CGP 2:227164565-227357836
CIL_00076U CIL_00076U_0001 CGP 2:227325151-227381995

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000266 ISS mitochondrial fission
GO:0001836 IMP release of cytochrome c from mitochondria
GO:0005515 IPI protein binding
GO:0005739 IEA mitochondrion
GO:0005741 IDA mitochondrial outer membrane
GO:0005777 IDA peroxisome
GO:0006626 IMP protein targeting to mitochondrion
GO:0008053 IMP mitochondrial fusion
GO:0010821 IMP regulation of mitochondrion organization
GO:0016559 IMP peroxisome fission
GO:0030054 IEA cell junction
GO:0031410 IEA cytoplasmic vesicle
GO:0032592 IDA integral component of mitochondrial membrane
GO:0042803 IDA protein homodimerization activity
GO:0043653 IMP mitochondrial fragmentation involved in apoptotic process
GO:0045202 IEA synapse
GO:0051260 IDA protein homooligomerization
GO:0070584 IMP mitochondrion morphogenesis
GO:0090141 IDA positive regulation of mitochondrial fission
GO:0090200 IMP positive regulation of release of cytochrome c from mitochondria
GO:0090314 IDA positive regulation of protein targeting to membrane
GO:1900063 IMP regulation of peroxisome organization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053753 mff mitochondrial fission factor protein_coding Danio_rerio
ENSMUSG00000026150 Mff mitochondrial fission factor protein_coding Mus_musculus

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