C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitochondrial fission factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026150 Mff 10090 + 1:82724890-82752394 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000073025 Mff-003 82724919-82752387 protein_coding
  ENSMUST00000078332 Mff-001 82724890-82752390 protein_coding
  ENSMUST00000159279 Mff-007 82729326-82741884 protein_coding
  ENSMUST00000160044 Mff-008 82729326-82750581 protein_coding
  ENSMUST00000160632 Mff-012 82741639-82751719 retained_intron
  ENSMUST00000160744 Mff-013 82735470-82752158 protein_coding
  ENSMUST00000160750 Mff-011 82729272-82751641 protein_coding
  ENSMUST00000160786 Mff-002 82724940-82752350 protein_coding
  ENSMUST00000160972 Mff-004 82729229-82752390 protein_coding
  ENSMUST00000161572 Mff-010 82724918-82735507 processed_transcript
  ENSMUST00000161648 Mff-009 82724925-82752390 protein_coding
  ENSMUST00000162003 Mff-005 82724948-82752394 protein_coding
  ENSMUST00000162056 Mff-006 82724934-82736728 retained_intron
  ENSMUST00000162573 Mff-015 82748389-82751728 retained_intron
  ENSMUST00000162794 Mff-014 82746923-82751886 retained_intron
  ENSMUST00000188333 Mff-016 82741978-82745895 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartLiverMuscleOvaryPlacentaTestisENSMUST00000073025ENSMUST00000078332ENSMUST00000159279ENSMUST00000160044ENSMUST00000160632ENSMUST00000160786ENSMUST00000160972ENSMUST00000161572ENSMUST00000162003ENSMUST00000162794ENSMUST00000188333
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Liver Muscle Ovary Placenta Testis
ENSMUST00000073025 8.654±0.87 N/A 11.872±1.41 23.814±3.40 7.311±2.42 4.265±0.00 N/A 9.008±4.52 8.878±0.00 7.986±2.74 10.498±0.86 16.826±0.96
ENSMUST00000078332 7.609±1.88 20.310±2.71 14.394±1.69 28.816±11.66 10.554±2.19 8.755±2.18 29.652±5.83 12.025±5.75 27.114±2.18 9.140±1.83 10.170±1.00 N/A
ENSMUST00000159279 N/A N/A N/A N/A 30.661±0.00 N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000160044 N/A N/A N/A N/A N/A N/A N/A N/A N/A 49.441±0.00 29.833±0.00 N/A
ENSMUST00000160632 N/A N/A N/A 39.260±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000160786 9.590±0.34 N/A 16.578±1.32 25.780±1.30 10.386±0.96 N/A 19.250±2.66 11.382±2.73 N/A 10.739±0.00 14.433±4.02 31.631±3.43
ENSMUST00000160972 N/A N/A 16.212±1.10 N/A N/A N/A N/A 20.281±4.87 N/A 23.660±1.64 9.740±4.25 N/A
ENSMUST00000161572 27.073±0.00 237.677±48.20 N/A N/A 25.780±3.72 29.312±5.57 N/A 15.812±1.88 N/A 44.957±18.61 30.061±0.01 N/A
ENSMUST00000162003 N/A N/A N/A N/A N/A N/A N/A N/A 14.675±1.14 N/A N/A N/A
ENSMUST00000162794 N/A N/A N/A 81.497±0.00 N/A N/A N/A N/A N/A 54.204±0.00 35.189±7.33 56.784±0.00
ENSMUST00000188333 N/A N/A N/A N/A 1.841±0.00 N/A N/A N/A N/A 2.382±0.51 2.229±1.23 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006XR CIL_0006XR_0002 CGP 1:82586921-82752394
CIL_00076U CIL_00076U_0002 CGP 1:82724890-82768461

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000266 IMP mitochondrial fission
GO:0001836 IEA release of cytochrome c from mitochondria
GO:0005515 IPI protein binding
GO:0005739 IDA mitochondrion
GO:0005741 IDA mitochondrial outer membrane
GO:0005777 IDA peroxisome
GO:0006626 IEA protein targeting to mitochondrion
GO:0008053 ISS mitochondrial fusion
GO:0010821 IEA regulation of mitochondrion organization
GO:0016559 IEA peroxisome fission
GO:0030054 IEA cell junction
GO:0031410 IEA cytoplasmic vesicle
GO:0032592 IEA integral component of mitochondrial membrane
GO:0042803 ISS protein homodimerization activity
GO:0043653 IEA mitochondrial fragmentation involved in apoptotic process
GO:0045202 IEA synapse
GO:0051260 IEA protein homooligomerization
GO:0070584 IEA mitochondrion morphogenesis
GO:0090141 ISS positive regulation of mitochondrial fission
GO:0090200 IEA positive regulation of release of cytochrome c from mitochondria
GO:0090314 ISS positive regulation of protein targeting to membrane
GO:1900063 IEA regulation of peroxisome organization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053753 mff mitochondrial fission factor protein_coding Danio_rerio
ENSG00000168958 MFF mitochondrial fission factor protein_coding Homo_sapiens

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