C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: regulator of G-protein signaling 14
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169220 RGS14 9606 + 5:177357837-177372601 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000408923 RGS14-001 177357837-177372601 protein_coding
  ENST00000425155 RGS14-003 177367314-177372596 retained_intron
  ENST00000502731 RGS14-014 177370553-177371578 retained_intron
  ENST00000503044 RGS14-012 177371107-177372143 retained_intron
  ENST00000503110 RGS14-007 177367217-177368888 processed_transcript
  ENST00000504631 RGS14-006 177366428-177367557 retained_intron
  ENST00000506944 RGS14-013 177371113-177372166 processed_transcript
  ENST00000509289 RGS14-011 177371066-177371582 retained_intron
  ENST00000511890 RGS14-002 177366943-177372298 protein_coding
  ENST00000512000 RGS14-009 177367302-177368016 retained_intron
  ENST00000512490 RGS14-008 177367303-177368804 retained_intron
  ENST00000514102 RGS14-010 177370821-177372292 retained_intron
  ENST00000514713 RGS14-004 177366943-177369075 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000408923ENST00000425155ENST00000502731ENST00000503044ENST00000503110ENST00000504631ENST00000506944ENST00000511890ENST00000512490ENST00000514102ENST00000514713
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000408923 N/A 3.364±0.00 N/A N/A N/A N/A N/A N/A 4.049±0.00 1.368±1.27 N/A 1.666±0.54 0.552±0.33 0.598±0.00
ENST00000425155 N/A 2.817±0.00 N/A N/A N/A 0.479±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000502731 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.742±0.00
ENST00000503044 2.561±0.00 N/A N/A N/A 2.277±0.00 2.171±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000503110 N/A N/A 0.338±0.00 N/A N/A N/A N/A N/A N/A 0.621±0.00 0.298±0.00 N/A N/A N/A
ENST00000504631 N/A N/A 0.372±0.00 N/A N/A N/A N/A N/A N/A N/A 1.373±0.00 N/A N/A N/A
ENST00000506944 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.485±0.00 2.463±0.00
ENST00000511890 0.718±0.00 8.982±0.00 0.557±0.00 4.541±0.00 1.424±0.00 1.427±0.00 N/A N/A 0.236±0.00 N/A N/A 3.543±1.52 0.965±0.00 3.093±0.00
ENST00000512490 N/A N/A N/A N/A 2.574±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000514102 N/A N/A N/A 2.184±1.17 0.928±0.48 0.253±0.00 0.366±0.16 6.146±0.00 0.191±0.00 N/A N/A N/A 1.313±0.00 1.721±0.00
ENST00000514713 N/A N/A N/A N/A 0.635±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008A2 CIL_0008A2_0001 VISTA 5:177089375-177692188
CIL_0002YL CIL_0002YL_0001 CGP 5:177331562-177372601
CIL_0002YI CIL_0002YI_0001 CGP 5:177357837-177398848

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000922 ISS spindle pole
GO:0001965 IEA G-protein alpha-subunit binding
GO:0005057 ISS:IEA receptor signaling protein activity
GO:0005092 IDA GDP-dissociation inhibitor activity
GO:0005096 IBA GTPase activator activity
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005813 ISS centrosome
GO:0005819 IDA spindle
GO:0005874 IEA microtubule
GO:0005886 ISS plasma membrane
GO:0006913 ISS nucleocytoplasmic transport
GO:0006979 ISS response to oxidative stress
GO:0007051 IMP spindle organization
GO:0007059 ISS chromosome segregation
GO:0007067 IEA mitotic nuclear division
GO:0007165 IEA signal transduction
GO:0007612 ISS learning
GO:0007616 ISS long-term memory
GO:0008017 IDA microtubule binding
GO:0008277 TAS:IEA regulation of G-protein coupled receptor protein signaling pathway
GO:0008542 ISS visual learning
GO:0010070 ISS zygote asymmetric cell division
GO:0014069 ISS postsynaptic density
GO:0016604 ISS nuclear body
GO:0019901 IEA protein kinase binding
GO:0030054 IEA cell junction
GO:0030159 ISS receptor signaling complex scaffold activity
GO:0030425 ISS dendrite
GO:0030695 IEA GTPase regulator activity
GO:0031914 ISS negative regulation of synaptic plasticity
GO:0032794 IEA GTPase activating protein binding
GO:0035556 IEA intracellular signal transduction
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0043197 ISS dendritic spine
GO:0043407 ISS negative regulation of MAP kinase activity
GO:0043547 IBA positive regulation of GTPase activity
GO:0043620 ISS regulation of DNA-templated transcription in response to stress
GO:0045211 IEA postsynaptic membrane
GO:0048008 ISS platelet-derived growth factor receptor signaling pathway
GO:0050769 ISS positive regulation of neurogenesis
GO:0051301 IMP cell division
GO:0060291 ISS long-term synaptic potentiation
GO:0070373 ISS negative regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021521 rgs14a regulator of G-protein signaling 14a protein_coding Danio_rerio
ENSDARG00000060200 RGS14 (2 of 2) regulator of G-protein signaling 14 protein_coding Danio_rerio
ENSMUSG00000052087 Rgs14 regulator of G-protein signaling 14 protein_coding Mus_musculus

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