C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: regulator of G-protein signaling 14
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000052087 Rgs14 10090 + 13:55369732-55384687 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000063771 Rgs14-001 55369732-55384687 protein_coding
  ENSMUST00000135851 Rgs14-002 55379169-55384686 retained_intron
  ENSMUST00000149858 Rgs14-003 55369771-55379445 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000063771ENSMUST00000135851ENSMUST00000149858
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000063771 1.627±0.34 0.692±0.28 1.010±0.15 1.221±1.47 11.294±3.00 2.410±0.29 0.486±0.30 0.777±0.54 1.062±1.04 4.608±0.63 0.263±0.30 1.078±0.38 0.237±0.17 0.059±0.01
ENSMUST00000135851 N/A N/A N/A 12.629±0.00 N/A 0.499±0.00 0.201±0.00 0.611±0.30 N/A N/A 0.209±0.13 0.181±0.00 0.172±0.08 0.041±0.01
ENSMUST00000149858 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.378±0.19 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008A2 CIL_0008A2_0002 VISTA 13:55104361-55707564
CIL_0002YL CIL_0002YL_0002 CGP 13:55343833-55384687
CIL_0002YI CIL_0002YI_0002 CGP 13:55369732-55414695

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000922 ISS spindle pole
GO:0001965 IEA G-protein alpha-subunit binding
GO:0005057 IDA receptor signaling protein activity
GO:0005092 ISS GDP-dissociation inhibitor activity
GO:0005096 IBA GTPase activator activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IBA cytoplasm
GO:0005813 IDA centrosome
GO:0005819 IDA spindle
GO:0005874 IEA microtubule
GO:0005886 IBA plasma membrane
GO:0006913 IDA nucleocytoplasmic transport
GO:0006979 ISS response to oxidative stress
GO:0007051 IMP spindle organization
GO:0007059 IMP chromosome segregation
GO:0007067 IMP mitotic nuclear division
GO:0007186 TAS G-protein coupled receptor signaling pathway
GO:0007612 IMP learning
GO:0007616 IMP long-term memory
GO:0008017 ISS microtubule binding
GO:0008277 IEA regulation of G-protein coupled receptor protein signaling pathway
GO:0008542 ISS visual learning
GO:0010070 IMP zygote asymmetric cell division
GO:0014069 IDA postsynaptic density
GO:0016604 IDA nuclear body
GO:0019901 IEA protein kinase binding
GO:0030054 IEA cell junction
GO:0030159 ISS receptor signaling complex scaffold activity
GO:0030425 IDA dendrite
GO:0031914 IMP negative regulation of synaptic plasticity
GO:0032794 IPI GTPase activating protein binding
GO:0035556 IEA intracellular signal transduction
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0043197 IDA dendritic spine
GO:0043407 IMP negative regulation of MAP kinase activity
GO:0043547 IBA positive regulation of GTPase activity
GO:0043620 IDA regulation of DNA-templated transcription in response to stress
GO:0045211 IEA postsynaptic membrane
GO:0048008 ISS platelet-derived growth factor receptor signaling pathway
GO:0050769 ISS positive regulation of neurogenesis
GO:0051301 ISS cell division
GO:0060291 IDA long-term synaptic potentiation
GO:0070373 ISS negative regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021521 rgs14a regulator of G-protein signaling 14a protein_coding Danio_rerio
ENSDARG00000060200 RGS14 (2 of 2) regulator of G-protein signaling 14 protein_coding Danio_rerio
ENSG00000169220 RGS14 regulator of G-protein signaling 14 protein_coding Homo_sapiens

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