C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chemokine (C-X-C motif) ligand 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169245 CXCL10 9606 - 4:76021117-76023497 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000306602 CXCL10-001 76021117-76023497 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000306602
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000306602 0.059±0.00 1.348±0.00 0.896±0.00 0.072±0.00 3.232±2.90 1.352±0.00 0.979±0.90 1.608±0.81 0.249±0.15 16.355±13.65 0.043±0.00 2.499±0.87 1.820±0.58 0.671±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00071M CIL_00071M_0001 CGP 4:76001275-76112802
CIL_00071H CIL_00071H_0001 CGP 4:76011184-76112802

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002690 IEA positive regulation of leukocyte chemotaxis
GO:0005102 TAS receptor binding
GO:0005515 IPI protein binding
GO:0005576 IDA:IEA extracellular region
GO:0005615 IEA extracellular space
GO:0006935 IDA chemotaxis
GO:0006954 IEA inflammatory response
GO:0006955 IEA immune response
GO:0007165 TAS signal transduction
GO:0007166 TAS cell surface receptor signaling pathway
GO:0007186 IMP G-protein coupled receptor signaling pathway
GO:0007267 TAS cell-cell signaling
GO:0007517 TAS muscle organ development
GO:0008009 IDA:IEA chemokine activity
GO:0008015 TAS blood circulation
GO:0008201 IMP heparin binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0008603 TAS cAMP-dependent protein kinase regulator activity
GO:0009306 IEA protein secretion
GO:0009409 IEA response to cold
GO:0009615 IEA response to virus
GO:0009897 IEA external side of plasma membrane
GO:0010332 IEA response to gamma radiation
GO:0010818 IMP T cell chemotaxis
GO:0010996 IEA response to auditory stimulus
GO:0016525 IEA negative regulation of angiogenesis
GO:0030335 IEA positive regulation of cell migration
GO:0030816 IDA positive regulation of cAMP metabolic process
GO:0032496 IEA response to lipopolysaccharide
GO:0033280 IEA response to vitamin D
GO:0034605 IEA cellular response to heat
GO:0042127 IDA regulation of cell proliferation
GO:0043950 IDA positive regulation of cAMP-mediated signaling
GO:0045662 IEA negative regulation of myoblast differentiation
GO:0045859 TAS regulation of protein kinase activity
GO:0045944 TAS positive regulation of transcription from RNA polymerase II promoter
GO:0048248 IDA CXCR3 chemokine receptor binding
GO:0051281 IDA positive regulation of release of sequestered calcium ion into cytosol
GO:0051607 IEA defense response to virus
GO:0070098 IMP chemokine-mediated signaling pathway
GO:0071222 IMP cellular response to lipopolysaccharide
GO:1901740 IEA negative regulation of myoblast fusion
GO:2000406 IDA positive regulation of T cell migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000034855 Cxcl10 chemokine (C-X-C motif) ligand 10 protein_coding Mus_musculus

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