C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: purinergic receptor P2Y, G-protein coupled, 12
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169313 P2RY12 9606 - 3:151337380-151384812 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000302632 P2RY12-001 151337380-151384812 protein_coding
  ENST00000468596 P2RY12-003 151338158-151340853 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartLiverLungMuscleOvaryPlacentaENST00000302632ENST00000468596
Transcript ID Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta
ENST00000302632 N/A 1.311±0.66 0.177±0.00 0.137±0.10 N/A 0.338±0.00 0.170±0.00 0.115±0.07 0.620±0.28
ENST00000468596 16.985±0.00 1.155±0.00 0.894±0.00 0.166±0.00 0.472±0.00 1.053±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002ID CIL_0002ID_0001 CGP 3:150926163-151437072
CIL_0002IE CIL_0002IE_0001 CGP 3:151085697-151437072
CIL_0002I6 CIL_0002I6_0001 CGP 3:151326312-151384812
CIL_0003H3 CIL_0003H3_0001 CGP 3:151337380-151458709

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001609 IEA G-protein coupled adenosine receptor activity
GO:0001621 IDA ADP receptor activity
GO:0001973 IEA adenosine receptor signaling pathway
GO:0004930 IEA G-protein coupled receptor activity
GO:0005085 TAS guanyl-nucleotide exchange factor activity
GO:0005739 IEA mitochondrion
GO:0005886 TAS plasma membrane
GO:0005901 IEA caveola
GO:0007186 IDA:IEA G-protein coupled receptor signaling pathway
GO:0007188 IEA adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007193 IMP adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007596 TAS blood coagulation
GO:0007599 NAS hemostasis
GO:0009897 IEA external side of plasma membrane
GO:0009925 IEA basal plasma membrane
GO:0009986 IDA cell surface
GO:0010700 IEA negative regulation of norepinephrine secretion
GO:0016021 IEA integral component of membrane
GO:0030030 IEA cell projection organization
GO:0030168 TAS platelet activation
GO:0031224 IDA intrinsic component of membrane
GO:0035589 IEA G-protein coupled purinergic nucleotide receptor signaling pathway
GO:0043270 IEA positive regulation of ion transport
GO:0043491 IEA protein kinase B signaling
GO:0043547 TAS positive regulation of GTPase activity
GO:0045596 IEA negative regulation of cell differentiation
GO:0051924 IEA regulation of calcium ion transport
GO:0070527 IMP platelet aggregation
GO:0070588 IEA calcium ion transmembrane transport
GO:0071805 IEA potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069945 p2ry12 purinergic receptor P2Y, G-protein coupled, 12 protein_coding Danio_rerio
ENSMUSG00000036353 P2ry12 purinergic receptor P2Y, G-protein coupled 12 protein_coding Mus_musculus

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