C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: purinergic receptor P2Y, G-protein coupled 12
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000036353 P2ry12 10090 - 3:59216271-59262831 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000050360 P2ry12-201 59216271-59262831 protein_coding
  ENSMUST00000170388 P2ry12-202 59216360-59220259 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000050360ENSMUST00000170388
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000050360 0.344±0.06 0.581±0.22 0.301±0.00 0.250±0.00 0.669±0.36 0.519±0.00 0.308±0.17 0.153±0.00 0.207±0.18 0.584±0.19 0.069±0.04 0.341±0.15 0.086±0.04 N/A
ENSMUST00000170388 1.254±0.26 1.151±0.50 0.495±0.04 1.271±0.91 2.348±0.59 1.230±0.30 0.619±0.29 0.223±0.16 0.778±0.48 0.998±0.29 0.173±0.08 0.576±0.35 0.128±0.11 0.117±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002ID CIL_0002ID_0002 CGP 3:58844028-59318410
CIL_0002IE CIL_0002IE_0002 CGP 3:59006978-59318410
CIL_0002I6 CIL_0002I6_0002 CGP 3:59207896-59262831
CIL_0003H3 CIL_0003H3_0002 CGP 3:59216271-59344256

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001609 IMP G-protein coupled adenosine receptor activity
GO:0001621 IMP ADP receptor activity
GO:0001973 IEA adenosine receptor signaling pathway
GO:0005739 IEA mitochondrion
GO:0005887 IC integral component of plasma membrane
GO:0005901 IEA caveola
GO:0007188 IMP adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007193 ISS adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0009897 IEA external side of plasma membrane
GO:0009925 IEA basal plasma membrane
GO:0009986 IEA cell surface
GO:0010700 IEA negative regulation of norepinephrine secretion
GO:0030030 IEA cell projection organization
GO:0030168 IMP platelet activation
GO:0031224 ISS intrinsic component of membrane
GO:0035589 IEA G-protein coupled purinergic nucleotide receptor signaling pathway
GO:0043270 IGI positive regulation of ion transport
GO:0043491 IEA protein kinase B signaling
GO:0045596 IEA negative regulation of cell differentiation
GO:0051924 IEA regulation of calcium ion transport
GO:0070527 ISS platelet aggregation
GO:0070588 IEA calcium ion transmembrane transport
GO:0071805 IEA potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069945 p2ry12 purinergic receptor P2Y, G-protein coupled, 12 protein_coding Danio_rerio
ENSG00000169313 P2RY12 purinergic receptor P2Y, G-protein coupled, 12 protein_coding Homo_sapiens

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