C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: platelet-activating factor receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169403 PTAFR 9606 - 1:28147166-28193936 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000305392 PTAFR-002 28149673-28193873 protein_coding
  ENST00000373857 PTAFR-001 28147166-28177188 protein_coding
  ENST00000539896 PTAFR-201 28147166-28193936 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderHeartKidneyLiverLungMuscleOvaryPlacentaENST00000305392ENST00000539896
Transcript ID Adipose Adrenal Bladder Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000305392 N/A N/A 0.354±0.00 0.174±0.00 0.383±0.00 N/A N/A 0.051±0.00 N/A N/A
ENST00000539896 1.808±0.00 0.592±0.00 N/A N/A N/A 0.625±0.00 2.161±0.00 0.105±0.00 1.204±0.76 3.013±0.30

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001530 IEA lipopolysaccharide binding
GO:0001816 IEA cytokine production
GO:0001875 IEA lipopolysaccharide receptor activity
GO:0004930 TAS:IEA G-protein coupled receptor activity
GO:0004992 IDA platelet activating factor receptor activity
GO:0005543 IDA phospholipid binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006935 IEA chemotaxis
GO:0006954 IEA inflammatory response
GO:0006955 TAS immune response
GO:0007186 IMP:IEA G-protein coupled receptor signaling pathway
GO:0016020 IDA membrane
GO:0016021 NAS:IEA integral component of membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0031663 IEA lipopolysaccharide-mediated signaling pathway
GO:0032496 IEA response to lipopolysaccharide
GO:0032959 IEA inositol trisphosphate biosynthetic process
GO:0048015 IDA phosphatidylinositol-mediated signaling
GO:0060333 TAS interferon-gamma-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042370 PTAFR platelet-activating factor receptor protein_coding Danio_rerio
ENSMUSG00000056529 Ptafr platelet-activating factor receptor protein_coding Mus_musculus

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