C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dopamine receptor D5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169676 DRD5 9606 + 4:9781680-9784009 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000304374 DRD5-001 9781680-9784009 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungOvaryTestisENST00000304374
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Testis
ENST00000304374 0.463±0.00 0.602±0.08 0.312±0.00 0.020±0.00 0.010±0.00 0.486±0.00 0.034±0.00 0.365±0.00 0.114±0.04 0.820±0.35

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001588 TAS dopamine neurotransmitter receptor activity, coupled via Gs
GO:0001963 NAS synaptic transmission, dopaminergic
GO:0001975 IEA response to amphetamine
GO:0001992 IEA regulation of systemic arterial blood pressure by vasopressin
GO:0001994 IEA norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
GO:0004930 IEA G-protein coupled receptor activity
GO:0004952 IDA dopamine neurotransmitter receptor activity
GO:0005886 IDA plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0006874 TAS cellular calcium ion homeostasis
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007189 IDA adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007190 TAS activation of adenylate cyclase activity
GO:0007191 IDA adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007268 NAS synaptic transmission
GO:0007617 IEA mating behavior
GO:0008306 IEA associative learning
GO:0010579 IEA positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
GO:0016021 IEA integral component of membrane
GO:0019226 IEA transmission of nerve impulse
GO:0031526 IEA brush border membrane
GO:0033861 IDA negative regulation of NAD(P)H oxidase activity
GO:0035240 IDA dopamine binding
GO:0042060 IEA wound healing
GO:0042220 IEA response to cocaine
GO:0045762 IDA positive regulation of adenylate cyclase activity
GO:0045776 IEA negative regulation of blood pressure
GO:0045924 IEA regulation of female receptivity
GO:0046960 IEA sensitization
GO:0060158 TAS phospholipase C-activating dopamine receptor signaling pathway
GO:0060292 IEA long term synaptic depression
GO:0071870 IDA cellular response to catecholamine stimulus
GO:0072593 IDA reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037576 DRD5 (1 of 2) dopamine receptor D5 protein_coding Danio_rerio
ENSDARG00000090669 DRD5 (2 of 2) dopamine receptor D5 protein_coding Danio_rerio
ENSMUSG00000039358 Drd5 dopamine receptor D5 protein_coding Mus_musculus

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