C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dopamine receptor D5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000039358 Drd5 10090 + 5:38319509-38322310 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000041646 Drd5-201 38319509-38322310 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonOvaryTestisENSMUST00000041646
Transcript ID Brain Breast Colon Ovary Testis
ENSMUST00000041646 0.361±0.37 0.017±0.00 0.021±0.00 0.074±0.00 0.142±0.06

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008QQ CIL_0008QQ_0002 VISTA 5:37760247-38361421
CIL_00096M CIL_00096M_0002 VISTA 5:37765055-38366694
CIL_0008ZA CIL_0008ZA_0002 VISTA 5:37806142-38406996
CIL_0008UW CIL_0008UW_0002 VISTA 5:38299839-38905514

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001588 IMP dopamine neurotransmitter receptor activity, coupled via Gs
GO:0001975 IGI response to amphetamine
GO:0001992 IGI regulation of systemic arterial blood pressure by vasopressin
GO:0001994 IMP norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
GO:0004952 IEA dopamine neurotransmitter receptor activity
GO:0005886 IEA plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0007189 IDA adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007191 IEA adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007617 IMP mating behavior
GO:0008306 IMP associative learning
GO:0010579 IEA positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
GO:0019226 IMP transmission of nerve impulse
GO:0031526 IDA brush border membrane
GO:0033861 IEA negative regulation of NAD(P)H oxidase activity
GO:0035240 IEA dopamine binding
GO:0042060 IMP wound healing
GO:0042220 IMP response to cocaine
GO:0045762 IEA positive regulation of adenylate cyclase activity
GO:0045776 IGI negative regulation of blood pressure
GO:0045924 IMP regulation of female receptivity
GO:0046960 IGI sensitization
GO:0060292 IMP long term synaptic depression
GO:0071870 IEA cellular response to catecholamine stimulus
GO:0072593 IEA reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037576 DRD5 (1 of 2) dopamine receptor D5 protein_coding Danio_rerio
ENSDARG00000090669 DRD5 (2 of 2) dopamine receptor D5 protein_coding Danio_rerio
ENSG00000169676 DRD5 dopamine receptor D5 protein_coding Homo_sapiens

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