C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin-conjugating enzyme E2E 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000170142 UBE2E1 9606 + 3:23805903-23891316 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000306627 UBE2E1-001 23805903-23891316 protein_coding
  ENST00000346855 UBE2E1-002 23805965-23891316 protein_coding
  ENST00000424381 UBE2E1-003 23810443-23891314 protein_coding
  ENST00000442670 UBE2E1-007 23807089-23889216 protein_coding
  ENST00000452012 UBE2E1-006 23811458-23891316 protein_coding
  ENST00000467766 UBE2E1-004 23810443-23889426 protein_coding
  ENST00000475680 UBE2E1-008 23810795-23891089 processed_transcript
  ENST00000481622 UBE2E1-012 23805984-23808835 processed_transcript
  ENST00000484048 UBE2E1-011 23805955-23807888 retained_intron
  ENST00000493707 UBE2E1-009 23866271-23890872 processed_transcript
  ENST00000495141 UBE2E1-005 23805966-23887789 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000306627ENST00000346855ENST00000424381ENST00000442670ENST00000467766ENST00000475680ENST00000484048ENST00000495141
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000306627 8.514±0.00 9.801±0.00 1.086±0.00 13.283±9.45 8.956±7.28 17.294±12.28 12.365±9.46 6.805±0.00 7.569±2.06 16.368±14.81 4.514±3.95 14.975±9.10 31.290±8.25 11.702±7.86
ENST00000346855 5.316±0.00 4.753±0.00 N/A N/A N/A N/A N/A 1.730±0.00 2.148±0.00 2.745±0.00 N/A N/A 3.869±0.00 N/A
ENST00000424381 3.160±0.00 9.502±0.00 N/A 8.979±4.34 4.092±0.00 11.515±0.00 2.209±0.00 3.850±1.50 1.737±0.00 N/A 4.235±0.36 10.371±1.94 6.092±0.00 18.228±0.00
ENST00000442670 N/A N/A N/A N/A N/A N/A N/A 2.815±0.00 4.749±0.00 N/A 5.681±3.46 12.306±0.00 N/A N/A
ENST00000467766 N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.485±0.00 N/A N/A N/A N/A
ENST00000475680 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.351±0.00
ENST00000484048 N/A N/A 1.446±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000495141 N/A N/A 1.422±0.00 N/A N/A N/A N/A N/A N/A 3.585±0.00 N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000151 IDA ubiquitin ligase complex
GO:0000209 IDA protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0006511 TAS ubiquitin-dependent protein catabolic process
GO:0007094 TAS mitotic spindle assembly checkpoint
GO:0008152 IEA metabolic process
GO:0010390 IDA histone monoubiquitination
GO:0016567 IDA protein ubiquitination
GO:0016881 IEA acid-amino acid ligase activity
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0032020 IDA ISG15-protein conjugation
GO:0033523 IDA histone H2B ubiquitination
GO:0042296 IDA ISG15 ligase activity
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0070936 IDA protein K48-linked ubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000021774 Ube2e1 ubiquitin-conjugating enzyme E2E 1 protein_coding Mus_musculus

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