C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: salt-inducible kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000170145 SIK2 9606 + 11:111602391-111730853 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000304987 SIK2-001 111602391-111730853 protein_coding
  ENST00000533868 SIK2-003 111718742-111720674 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000304987
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000304987 29.401±0.00 3.019±0.00 2.102±0.00 6.130±1.44 14.210±10.24 3.465±0.49 3.064±1.73 5.695±0.90 5.323±0.20 7.359±2.10 11.315±4.24 4.124±2.29 2.739±0.46 4.111±0.70

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IDA:IEA magnesium ion binding
GO:0004672 IEA protein kinase activity
GO:0004674 IDA:IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0006468 IDA:IEA protein phosphorylation
GO:0008286 IEA insulin receptor signaling pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0035556 IDA:IEA intracellular signal transduction
GO:0046626 ISS regulation of insulin receptor signaling pathway
GO:0046777 IDA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062315 sik2b salt-inducible kinase 2b protein_coding Danio_rerio
ENSDARG00000079618 sik2a salt-inducible kinase 2a protein_coding Danio_rerio
ENSMUSG00000037112 Sik2 salt inducible kinase 2 protein_coding Mus_musculus

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