C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: salt inducible kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037112 Sik2 10090 - 9:50892801-51009073 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000041375 Sik2-001 50892801-51009073 protein_coding
  ENSMUST00000068484 Sik2-004 50928264-51009026 processed_transcript
  ENSMUST00000176327 Sik2-008 50995584-51009011 retained_intron
  ENSMUST00000176491 Sik2-002 50892801-51008973 nonsense_mediated_decay
  ENSMUST00000176663 Sik2-007 50892801-51008936 protein_coding
  ENSMUST00000176824 Sik2-006 50892801-51008936 protein_coding
  ENSMUST00000177203 Sik2-003 50930562-51008984 processed_transcript
  ENSMUST00000177346 Sik2-005 50933836-51009000 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000041375ENSMUST00000068484ENSMUST00000176327ENSMUST00000176491ENSMUST00000176663ENSMUST00000176824
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000041375 22.899±15.05 11.809±2.41 N/A N/A 15.844±4.68 4.429±1.33 1.930±0.87 3.785±0.70 1.552±0.41 3.862±0.50 N/A 6.685±2.36 N/A 7.061±0.60
ENSMUST00000068484 N/A 70.190±26.09 N/A N/A 83.482±0.00 N/A N/A N/A N/A N/A N/A 31.621±3.78 N/A N/A
ENSMUST00000176327 N/A 79.025±8.05 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000176491 N/A N/A N/A N/A N/A N/A 1.216±0.00 N/A N/A N/A N/A N/A N/A 8.396±0.62
ENSMUST00000176663 26.581±9.81 7.263±2.74 3.351±0.12 3.886±1.04 15.187±0.00 3.739±0.40 1.724±0.32 N/A 2.581±1.62 4.389±0.00 3.324±0.00 4.860±1.85 2.315±0.43 N/A
ENSMUST00000176824 13.429±4.69 5.729±0.69 2.625±0.44 1.767±0.13 9.069±0.21 2.138±0.17 1.032±0.19 2.260±0.47 N/A N/A N/A 3.490±0.79 1.122±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003WK CIL_0003WK_0002 CGP 9:50775019-50894229
CIL_0003WH CIL_0003WH_0003 CGP 9:50845301-51009073
CIL_0003WI CIL_0003WI_0003 CGP 9:50892801-51077094

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0004674 IDA protein serine/threonine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0006468 IDA protein phosphorylation
GO:0008286 IDA insulin receptor signaling pathway
GO:0035556 IEA intracellular signal transduction
GO:0046777 IEA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062315 sik2b salt-inducible kinase 2b protein_coding Danio_rerio
ENSDARG00000079618 sik2a salt-inducible kinase 2a protein_coding Danio_rerio
ENSG00000170145 SIK2 salt-inducible kinase 2 protein_coding Homo_sapiens

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