C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000170525 PFKFB3 9606 + 10:6144934-6235545 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000317350 PFKFB3-015 6202866-6228284 protein_coding
  ENST00000360521 PFKFB3-006 6202900-6232959 protein_coding
  ENST00000379775 PFKFB3-002 6202931-6235532 protein_coding
  ENST00000379785 PFKFB3-010 6202866-6233090 protein_coding
  ENST00000379789 PFKFB3-001 6144934-6235532 protein_coding
  ENST00000414237 PFKFB3-005 6224166-6233090 protein_coding
  ENST00000441697 PFKFB3-011 6224166-6233090 protein_coding
  ENST00000450232 PFKFB3-013 6221404-6233107 protein_coding
  ENST00000461744 PFKFB3-012 6202866-6228295 nonsense_mediated_decay
  ENST00000467491 PFKFB3-008 6202866-6232952 nonsense_mediated_decay
  ENST00000475881 PFKFB3-004 6224166-6233090 nonsense_mediated_decay
  ENST00000477914 PFKFB3-009 6202866-6232959 nonsense_mediated_decay
  ENST00000487989 PFKFB3-014 6222708-6226447 retained_intron
  ENST00000490474 PFKFB3-007 6202866-6232959 nonsense_mediated_decay
  ENST00000536985 PFKFB3-201 6146316-6235545 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000360521ENST00000379775ENST00000379789
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000360521 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.552±0.00 N/A 2.181±0.00 N/A N/A
ENST00000379775 115.535±0.00 2.814±0.00 2.869±0.00 10.086±0.00 57.101±55.73 3.267±1.78 3.320±0.00 58.406±0.00 3.958±0.41 17.780±14.19 124.137±0.00 3.353±1.50 4.003±0.95 1.790±0.02
ENST00000379789 51.635±0.00 4.039±0.00 N/A 14.037±6.38 19.865±0.00 5.973±5.52 2.378±0.00 0.770±0.00 0.851±0.00 14.452±0.00 N/A 9.263±4.12 3.995±0.45 6.788±1.29

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003873 IEA 6-phosphofructo-2-kinase activity
GO:0004331 IEA fructose-2,6-bisphosphate 2-phosphatase activity
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005829 TAS cytosol
GO:0005975 TAS carbohydrate metabolic process
GO:0006000 IEA fructose metabolic process
GO:0006003 IEA fructose 2,6-bisphosphate metabolic process
GO:0006006 TAS glucose metabolic process
GO:0006096 TAS glycolytic process
GO:0007420 IEA brain development
GO:0016311 IEA dephosphorylation
GO:0044281 TAS small molecule metabolic process
GO:0046835 IEA carbohydrate phosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001953 pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 protein_coding Danio_rerio
ENSMUSG00000026773 Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 protein_coding Mus_musculus

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