C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026773 Pfkfb3 10090 - 2:11471430-11502101 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028114 Pfkfb3-001 11471430-11502067 protein_coding
  ENSMUST00000049849 Pfkfb3-003 11479900-11502075 protein_coding
  ENSMUST00000100411 Pfkfb3-006 11477967-11502101 protein_coding
  ENSMUST00000114844 Pfkfb3-005 11477955-11502101 protein_coding
  ENSMUST00000114845 Pfkfb3-201 11475764-11502090 protein_coding
  ENSMUST00000114846 Pfkfb3-002 11471430-11502025 protein_coding
  ENSMUST00000140580 Pfkfb3-010 11492610-11498351 processed_transcript
  ENSMUST00000144921 Pfkfb3-008 11493903-11501296 processed_transcript
  ENSMUST00000145970 Pfkfb3-009 11493906-11500862 processed_transcript
  ENSMUST00000150086 Pfkfb3-007 11480190-11494030 processed_transcript
  ENSMUST00000155167 Pfkfb3-011 11492310-11501797 processed_transcript
  ENSMUST00000170196 Pfkfb3-202 11474537-11502090 protein_coding
  ENSMUST00000171188 Pfkfb3-203 11475764-11502090 protein_coding
  ENSMUST00000179584 Pfkfb3-204 11471433-11502090 protein_coding
  ENSMUST00000183869 Pfkfb3-004 11471828-11498385 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028114ENSMUST00000049849ENSMUST00000100411ENSMUST00000114845ENSMUST00000114846ENSMUST00000170196ENSMUST00000179584ENSMUST00000183869
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028114 N/A N/A N/A 5.262±3.37 N/A N/A N/A N/A N/A N/A 17.562±0.00 2.630±0.00 0.320±0.00 N/A
ENSMUST00000049849 N/A N/A N/A N/A N/A N/A 0.946±0.00 N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000100411 N/A N/A N/A N/A N/A 0.776±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000114845 N/A N/A N/A N/A N/A 1.591±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000114846 91.831±56.87 17.754±7.52 7.980±0.25 3.249±1.49 57.551±10.41 2.012±0.35 2.411±1.54 5.807±1.05 2.762±2.52 15.003±4.44 37.218±21.27 16.061±6.94 2.505±2.41 N/A
ENSMUST00000170196 N/A 12.168±0.70 N/A N/A 20.066±0.00 1.487±0.00 N/A N/A N/A N/A N/A N/A N/A 1.738±0.00
ENSMUST00000179584 N/A 5.948±1.42 1.611±0.00 1.435±0.98 45.940±32.28 0.628±0.16 0.808±0.16 1.534±0.26 0.460±0.13 6.225±1.33 N/A 6.897±3.34 1.065±0.51 N/A
ENSMUST00000183869 N/A N/A N/A N/A N/A 1.817±0.00 N/A N/A N/A N/A N/A N/A N/A 14.274±3.06

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000QE CIL_0000QE_0002 CGP 2:11172113-11502101
CIL_0000QD CIL_0000QD_0002 CGP 2:11471430-11604153

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003873 IEA 6-phosphofructo-2-kinase activity
GO:0004331 IEA fructose-2,6-bisphosphate 2-phosphatase activity
GO:0005524 IEA ATP binding
GO:0006000 IEA fructose metabolic process
GO:0006003 IEA fructose 2,6-bisphosphate metabolic process
GO:0016311 IEA dephosphorylation
GO:0046835 IEA carbohydrate phosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001953 pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 protein_coding Danio_rerio
ENSG00000170525 PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 protein_coding Homo_sapiens

Loading