C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: A kinase (PRKA) anchor protein 13
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000170776 AKAP13 9606 + 15:85380571-85749358 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000361243 AKAP13-001 85380729-85745610 protein_coding
  ENST00000394510 AKAP13-201 85619950-85749358 protein_coding
  ENST00000394518 AKAP13-004 85380715-85749355 protein_coding
  ENST00000557852 AKAP13-015 85689869-85715901 protein_coding
  ENST00000558009 AKAP13-019 85719212-85722302 retained_intron
  ENST00000558092 AKAP13-014 85683527-85684955 processed_transcript
  ENST00000558166 AKAP13-009 85544040-85579184 protein_coding
  ENST00000558644 AKAP13-023 85717152-85727247 retained_intron
  ENST00000558811 AKAP13-010 85555446-85579131 protein_coding
  ENST00000559278 AKAP13-017 85710443-85717391 retained_intron
  ENST00000559362 AKAP13-002 85380587-85684874 protein_coding
  ENST00000559391 AKAP13-022 85735599-85740562 retained_intron
  ENST00000559486 AKAP13-012 85645919-85669828 protein_coding
  ENST00000559820 AKAP13-018 85718801-85719322 processed_transcript
  ENST00000560185 AKAP13-021 85747604-85749156 processed_transcript
  ENST00000560256 AKAP13-006 85380756-85521508 protein_coding
  ENST00000560302 AKAP13-003 85380640-85536997 protein_coding
  ENST00000560340 AKAP13-011 85582910-85645917 protein_coding
  ENST00000560482 AKAP13-016 85693099-85717348 retained_intron
  ENST00000560571 AKAP13-005 85380571-85382170 processed_transcript
  ENST00000560579 AKAP13-008 85635097-85744677 protein_coding
  ENST00000560676 AKAP13-007 85619696-85727414 protein_coding
  ENST00000560957 AKAP13-013 85682168-85685446 retained_intron
  ENST00000612418 AKAP13-025 85677037-85693451 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000394510ENST00000394518ENST00000558644ENST00000559362ENST00000560579ENST00000560676
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000394510 3.471±0.00 N/A 2.599±0.00 N/A 2.495±0.00 5.094±0.25 N/A N/A 7.177±0.00 12.731±0.00 2.976±1.12 2.070±0.67 2.945±0.49
ENST00000394518 1.769±0.00 2.306±0.00 0.808±0.00 N/A 2.167±0.00 1.874±0.36 8.058±0.65 1.098±0.00 2.837±0.00 5.473±2.27 2.764±1.91 1.872±0.19 1.445±0.00
ENST00000558644 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.064±0.00 15.657±0.00 19.398±0.00
ENST00000559362 N/A N/A 3.424±0.00 N/A 6.929±0.00 11.115±0.00 9.297±0.00 N/A 8.671±0.00 N/A 8.210±0.00 N/A N/A
ENST00000560579 N/A N/A N/A N/A N/A N/A N/A 3.830±0.00 N/A N/A N/A N/A 3.668±0.00
ENST00000560676 N/A N/A N/A 2.135±0.00 10.691±0.00 N/A N/A N/A N/A N/A 8.512±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001RM CIL_0001RM_0001 CGP 15:85380571-85795030

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004691 IEA:NAS cAMP-dependent protein kinase activity
GO:0004871 TAS signal transducer activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006468 IEA protein phosphorylation
GO:0007264 TAS small GTPase mediated signal transduction
GO:0010611 IEA regulation of cardiac muscle hypertrophy
GO:0016020 IDA membrane
GO:0017048 IEA Rho GTPase binding
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0032947 IEA protein complex scaffold
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0035556 IEA intracellular signal transduction
GO:0043065 TAS positive regulation of apoptotic process
GO:0045859 IEA regulation of protein kinase activity
GO:0046872 IEA metal ion binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048471 IEA perinuclear region of cytoplasm
GO:0051018 IEA protein kinase A binding
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0051168 IEA nuclear export
GO:0097190 TAS apoptotic signaling pathway
GO:1900169 IEA regulation of glucocorticoid mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000023868 AKAP13 (1 of 2) A kinase (PRKA) anchor protein 13 protein_coding Danio_rerio
ENSDARG00000079358 AKAP13 (2 of 2) A kinase (PRKA) anchor protein 13 protein_coding Danio_rerio
ENSMUSG00000066406 Akap13 A kinase (PRKA) anchor protein 13 protein_coding Mus_musculus

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