C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: BCL2-like 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000171552 BCL2L1 9606 - 20:31664452-31723989 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000307677 BCL2L1-004 31664452-31722898 protein_coding
  ENST00000376055 BCL2L1-002 31664452-31722860 protein_coding
  ENST00000376062 BCL2L1-001 31664452-31722597 protein_coding
  ENST00000420488 BCL2L1-006 31721655-31723989 protein_coding
  ENST00000422920 BCL2L1-008 31721655-31723098 protein_coding
  ENST00000434194 BCL2L1-009 31722073-31722548 protein_coding
  ENST00000439267 BCL2L1-005 31721676-31723989 protein_coding
  ENST00000450273 BCL2L1-003 31666035-31723900 protein_coding
  ENST00000456404 BCL2L1-007 31721655-31723954 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000307677ENST00000376055ENST00000376062ENST00000422920ENST00000434194ENST00000450273
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000307677 48.059±0.00 27.348±0.00 5.945±0.00 16.801±0.00 9.373±3.41 16.803±12.27 12.198±11.47 15.025±10.33 13.459±8.68 29.671±24.76 6.319±0.00 21.621±20.59 39.059±13.89 23.884±4.30
ENST00000376055 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.418±0.00 N/A N/A N/A
ENST00000376062 N/A N/A 1.641±0.00 2.322±0.00 N/A 0.989±0.00 1.175±0.00 1.333±0.00 N/A 2.602±0.00 N/A N/A N/A N/A
ENST00000422920 N/A N/A 4.012±0.00 N/A 8.661±0.00 3.290±0.00 3.022±0.00 3.058±0.00 4.779±0.00 4.312±0.00 N/A 13.515±0.00 N/A 29.398±0.00
ENST00000434194 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.645±0.00 N/A N/A N/A
ENST00000450273 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 123.602±0.00 72.492±0.00 61.231±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008K5 CIL_0008K5_0001 VISTA 20:31303913-31904751
CIL_00089Z CIL_00089Z_0001 VISTA 20:31373735-31977079
CIL_0008N4 CIL_0008N4_0001 VISTA 20:31410024-32010895
CIL_0004MW CIL_0004MW_0002 CGP 20:31637888-31723989
CIL_0001A2 CIL_0001A2_0001 CGP 20:31664452-31801805

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000910 IMP cytokinesis
GO:0001541 IEA ovarian follicle development
GO:0001701 IEA in utero embryonic development
GO:0001836 IDA release of cytochrome c from mitochondria
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005741 NAS mitochondrial outer membrane
GO:0005743 IEA mitochondrial inner membrane
GO:0005813 IDA centrosome
GO:0005829 IEA cytosol
GO:0006897 IEA endocytosis
GO:0006915 TAS apoptotic process
GO:0007093 IMP mitotic cell cycle checkpoint
GO:0007281 IEA germ cell development
GO:0007283 IEA spermatogenesis
GO:0008283 IEA cell proliferation
GO:0008284 IEA positive regulation of cell proliferation
GO:0008584 IEA male gonad development
GO:0008630 IEA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0008637 TAS apoptotic mitochondrial changes
GO:0009314 IEA response to radiation
GO:0009566 IEA fertilization
GO:0009615 IEA response to virus
GO:0010507 TAS negative regulation of autophagy
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019050 IDA suppression by virus of host apoptotic process
GO:0019901 IPI protein kinase binding
GO:0030054 IEA cell junction
GO:0031410 IEA cytoplasmic vesicle
GO:0031966 IEA mitochondrial membrane
GO:0034097 IDA response to cytokine
GO:0035872 TAS nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0040007 IEA growth
GO:0042802 IPI identical protein binding
GO:0042803 IBA protein homodimerization activity
GO:0042981 IEA regulation of apoptotic process
GO:0043065 IEA positive regulation of apoptotic process
GO:0043066 IMP negative regulation of apoptotic process
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0045087 TAS innate immune response
GO:0045202 IEA synapse
GO:0046898 IEA response to cycloheximide
GO:0046902 IDA regulation of mitochondrial membrane permeability
GO:0046982 IBA protein heterodimerization activity
GO:0051402 IEA neuron apoptotic process
GO:0051434 IPI BH3 domain binding
GO:0051881 IDA regulation of mitochondrial membrane potential
GO:0060154 IEA cellular process regulating host cell cycle in response to virus
GO:0070584 IEA mitochondrion morphogenesis
GO:0071230 IEA cellular response to amino acid stimulus
GO:0071312 IEA cellular response to alkaloid
GO:0071480 IEA cellular response to gamma radiation
GO:0071839 IEA apoptotic process in bone marrow
GO:0090005 IDA negative regulation of establishment of protein localization to plasma membrane
GO:0090201 IDA negative regulation of release of cytochrome c from mitochondria
GO:0097136 IDA Bcl-2 family protein complex
GO:0097192 IBA extrinsic apoptotic signaling pathway in absence of ligand
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:0097284 IEA hepatocyte apoptotic process
GO:1900118 IDA negative regulation of execution phase of apoptosis
GO:1902230 IDA negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:2000811 IMP negative regulation of anoikis
GO:2001240 TAS negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO:2001243 IDA negative regulation of intrinsic apoptotic signaling pathway
GO:2001244 TAS positive regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008434 bcl2l1 bcl2-like 1 protein_coding Danio_rerio
ENSMUSG00000007659 Bcl2l1 BCL2-like 1 protein_coding Mus_musculus

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