C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fibrinogen gamma chain
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000171557 FGG 9606 - 4:154604134-154612967 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336098 FGG-002 154604576-154612648 protein_coding
  ENST00000393846 FGG-009 154609630-154612797 protein_coding
  ENST00000404648 FGG-001 154604134-154612849 protein_coding
  ENST00000405164 FGG-006 154604173-154612643 protein_coding
  ENST00000407946 FGG-007 154604610-154612635 protein_coding
  ENST00000443553 FGG-008 154608639-154612967 protein_coding
  ENST00000464532 FGG-012 154609943-154612656 retained_intron
  ENST00000465336 FGG-010 154611839-154612656 retained_intron
  ENST00000465913 FGG-003 154604171-154609843 retained_intron
  ENST00000473393 FGG-011 154611236-154612635 retained_intron
  ENST00000484695 FGG-005 154611973-154612611 retained_intron
  ENST00000492082 FGG-004 154604165-154612659 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000336098ENST00000393846ENST00000404648ENST00000405164ENST00000407946ENST00000464532ENST00000465913ENST00000492082
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000336098 N/A 0.048±0.00 N/A N/A N/A N/A 0.137±0.00 4.963±0.00 N/A 21.250±0.00 N/A 0.685±0.00 0.857±0.20 0.284±0.20
ENST00000393846 N/A N/A N/A N/A 0.016±0.00 N/A 0.106±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000404648 N/A N/A N/A N/A 2.522±0.00 N/A N/A 408.895±395.64 N/A 43.380±0.00 N/A 2.243±1.06 3.283±1.30 N/A
ENST00000405164 0.038±0.00 0.431±0.00 0.211±0.00 0.209±0.17 1.181±0.00 0.066±0.00 N/A 554.693±541.51 0.220±0.00 34.473±33.84 0.790±0.77 0.935±0.00 2.473±0.10 0.927±0.00
ENST00000407946 0.018±0.00 N/A N/A N/A N/A N/A 0.178±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000464532 N/A N/A N/A N/A N/A N/A N/A N/A 0.176±0.00 N/A N/A N/A N/A N/A
ENST00000465913 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.104±0.00 N/A 0.148±0.12 N/A N/A
ENST00000492082 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.049±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008D1 CIL_0008D1_0001 VISTA 4:154359551-154960904

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002576 TAS platelet degranulation
GO:0005102 IEA:IPI receptor binding
GO:0005198 IDA structural molecule activity
GO:0005576 TAS extracellular region
GO:0005577 IEA:IDA fibrinogen complex
GO:0005615 IDA extracellular space
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0005938 IEA cell cortex
GO:0007160 IDA cell-matrix adhesion
GO:0007165 IEA signal transduction
GO:0007596 TAS blood coagulation
GO:0009897 IDA external side of plasma membrane
GO:0009986 IDA cell surface
GO:0030168 IEA:TAS platelet activation
GO:0030198 TAS extracellular matrix organization
GO:0030674 IEA protein binding, bridging
GO:0031091 IDA platelet alpha granule
GO:0031093 TAS platelet alpha granule lumen
GO:0034116 IDA positive regulation of heterotypic cell-cell adhesion
GO:0043623 IDA cellular protein complex assembly
GO:0045907 IDA positive regulation of vasoconstriction
GO:0045921 IDA positive regulation of exocytosis
GO:0046872 IEA metal ion binding
GO:0050714 IDA positive regulation of protein secretion
GO:0050839 IPI cell adhesion molecule binding
GO:0051258 IEA:IMP protein polymerization
GO:0051592 IDA response to calcium ion
GO:0070062 IDA extracellular vesicular exosome
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade
GO:0070527 IDA platelet aggregation
GO:0072562 IDA blood microparticle
GO:0090277 IDA positive regulation of peptide hormone secretion
GO:1900026 NAS positive regulation of substrate adhesion-dependent cell spreading
GO:1902042 IDA negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2000352 IDA negative regulation of endothelial cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037281 fgg fibrinogen, gamma polypeptide protein_coding Danio_rerio
ENSMUSG00000033860 Fgg fibrinogen gamma chain protein_coding Mus_musculus

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