C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000171608 PIK3CD 9606 + 1:9651732-9729114 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000361110 PIK3CD-003 9710198-9727232 protein_coding
  ENST00000377346 PIK3CD-001 9651745-9728919 protein_coding
  ENST00000479223 PIK3CD-006 9716276-9717581 retained_intron
  ENST00000481137 PIK3CD-005 9715699-9716163 retained_intron
  ENST00000484851 PIK3CD-004 9688176-9691946 processed_transcript
  ENST00000536656 PIK3CD-201 9651732-9729114 protein_coding
  ENST00000543390 PIK3CD-202 9710198-9727227 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalKidneyLiverLungTestisENST00000377346ENST00000536656
Transcript ID Adrenal Kidney Liver Lung Testis
ENST00000377346 18.628±0.00 0.447±0.00 0.720±0.00 8.538±0.00 3.604±0.00
ENST00000536656 N/A 0.503±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008VW CIL_0008VW_0001 VISTA 1:9071068-9672775

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001779 TAS natural killer cell differentiation
GO:0001782 IEA B cell homeostasis
GO:0001816 TAS cytokine production
GO:0002250 TAS adaptive immune response
GO:0002551 TAS mast cell chemotaxis
GO:0002679 TAS respiratory burst involved in defense response
GO:0005488 IEA binding
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0005942 NAS phosphatidylinositol 3-kinase complex
GO:0006468 NAS protein phosphorylation
GO:0006644 TAS phospholipid metabolic process
GO:0006661 TAS phosphatidylinositol biosynthetic process
GO:0006954 TAS inflammatory response
GO:0007165 NAS signal transduction
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0010818 TAS T cell chemotaxis
GO:0014065 TAS phosphatidylinositol 3-kinase signaling
GO:0016301 IEA kinase activity
GO:0016303 NAS 1-phosphatidylinositol-3-kinase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0030101 TAS natural killer cell activation
GO:0030217 TAS T cell differentiation
GO:0030593 TAS neutrophil chemotaxis
GO:0035004 TAS phosphatidylinositol 3-kinase activity
GO:0035005 IBA 1-phosphatidylinositol-4-phosphate 3-kinase activity
GO:0035747 TAS natural killer cell chemotaxis
GO:0035754 TAS B cell chemotaxis
GO:0036092 NAS phosphatidylinositol-3-phosphate biosynthetic process
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042110 TAS T cell activation
GO:0042113 TAS B cell activation
GO:0042629 TAS mast cell granule
GO:0043303 TAS mast cell degranulation
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0046854 IEA phosphatidylinositol phosphorylation
GO:0046934 IBA phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 IEA phosphatidylinositol-mediated signaling
GO:0050852 TAS T cell receptor signaling pathway
GO:0050853 TAS B cell receptor signaling pathway
GO:0060374 TAS mast cell differentiation
GO:0072672 TAS neutrophil extravasation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003250 pik3cd phosphoinositide-3-kinase, catalytic, delta polypeptide protein_coding Danio_rerio
ENSMUSG00000039936 Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide protein_coding Mus_musculus

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