C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphatidylinositol 3-kinase catalytic delta polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000039936 Pik3cd 10090 - 4:149649168-149702571 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000038859 Pik3cd-003 149649168-149698698 protein_coding
  ENSMUST00000105688 Pik3cd-013 149649817-149698605 protein_coding
  ENSMUST00000105689 Pik3cd-002 149650640-149663284 protein_coding
  ENSMUST00000105690 Pik3cd-001 149649168-149698708 protein_coding
  ENSMUST00000118704 Pik3cd-007 149649171-149676044 protein_coding
  ENSMUST00000122059 Pik3cd-012 149649170-149701590 protein_coding
  ENSMUST00000124510 Pik3cd-006 149673765-149701590 processed_transcript
  ENSMUST00000127273 Pik3cd-005 149659778-149675186 protein_coding
  ENSMUST00000131224 Pik3cd-004 149659857-149675625 protein_coding
  ENSMUST00000134534 Pik3cd-010 149660184-149698552 protein_coding
  ENSMUST00000137430 Pik3cd-008 149673439-149676093 processed_transcript
  ENSMUST00000146612 Pik3cd-009 149660019-149698604 protein_coding
  ENSMUST00000156309 Pik3cd-011 149663153-149702571 protein_coding
  ENSMUST00000177654 Pik3cd-201 149649170-149674194 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000038859ENSMUST00000105688ENSMUST00000105689ENSMUST00000105690ENSMUST00000118704ENSMUST00000122059ENSMUST00000177654
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000038859 1.533±0.62 N/A 0.535±0.26 1.032±0.25 6.045±2.38 0.429±0.02 0.630±0.00 0.538±0.14 0.750±0.20 2.304±0.39 0.914±0.12 1.826±0.46 0.798±0.33 2.720±0.76
ENSMUST00000105688 N/A N/A N/A N/A N/A 1.168±0.00 N/A 0.483±0.00 N/A N/A N/A N/A N/A N/A
ENSMUST00000105689 N/A 0.398±0.00 N/A N/A N/A N/A 0.250±0.00 N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000105690 1.079±0.00 0.641±0.00 0.283±0.00 N/A N/A N/A 0.630±0.00 0.274±0.00 0.648±0.26 N/A N/A 1.851±0.00 N/A N/A
ENSMUST00000118704 0.742±0.00 N/A 0.469±0.16 2.183±0.04 N/A 0.584±0.00 0.510±0.11 N/A N/A N/A N/A 1.374±0.18 0.621±0.20 4.606±1.79
ENSMUST00000122059 1.286±0.49 0.286±0.00 0.708±0.15 1.145±0.00 7.040±3.99 0.615±0.12 0.216±0.00 0.719±0.43 0.860±0.63 2.560±0.69 1.307±0.44 2.539±0.75 1.098±0.00 2.619±0.83
ENSMUST00000177654 N/A 0.333±0.01 0.725±0.00 1.289±0.50 5.601±1.72 0.607±0.00 0.206±0.00 0.462±0.05 0.167±0.01 2.129±0.23 2.128±0.90 3.052±1.29 1.495±0.97 4.247±2.41

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008VW CIL_0008VW_0002 VISTA 4:149592945-150194331

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001782 IMP B cell homeostasis
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005886 IBA plasma membrane
GO:0005942 IBA phosphatidylinositol 3-kinase complex
GO:0006935 IEA chemotaxis
GO:0006954 IEA inflammatory response
GO:0007166 IMP cell surface receptor signaling pathway
GO:0016303 IBA 1-phosphatidylinositol-3-kinase activity
GO:0030154 IEA cell differentiation
GO:0035005 IBA 1-phosphatidylinositol-4-phosphate 3-kinase activity
GO:0036092 IBA phosphatidylinositol-3-phosphate biosynthetic process
GO:0042113 IMP B cell activation
GO:0045087 IEA innate immune response
GO:0046854 IEA phosphatidylinositol phosphorylation
GO:0046934 IBA phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0048015 IEA phosphatidylinositol-mediated signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003250 pik3cd phosphoinositide-3-kinase, catalytic, delta polypeptide protein_coding Danio_rerio
ENSG00000171608 PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta protein_coding Homo_sapiens

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