C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CTP synthase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000171793 CTPS1 9606 + 1:40979335-41012565 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000372616 CTPS1-002 40983161-41011779 protein_coding
  ENST00000372621 CTPS1-001 40979335-41012565 protein_coding
  ENST00000463285 CTPS1-011 40995980-41004250 processed_transcript
  ENST00000463423 CTPS1-012 41003156-41010254 processed_transcript
  ENST00000464283 CTPS1-010 41001539-41009589 processed_transcript
  ENST00000470271 CTPS1-003 40980108-40984988 processed_transcript
  ENST00000475060 CTPS1-004 40980585-40983445 processed_transcript
  ENST00000479480 CTPS1-005 40981927-40991821 processed_transcript
  ENST00000480420 CTPS1-006 40988497-41001114 processed_transcript
  ENST00000486889 CTPS1-008 40997125-41002236 processed_transcript
  ENST00000497210 CTPS1-009 41000813-41003176 processed_transcript
  ENST00000498694 CTPS1-013 41006064-41011754 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000372616ENST00000372621ENST00000463423ENST00000464283ENST00000479480ENST00000498694
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000372616 N/A N/A N/A N/A N/A N/A N/A N/A 0.806±0.00 N/A N/A 2.679±0.00 2.006±0.00 5.729±0.00
ENST00000372621 1.895±0.00 5.021±0.00 N/A 1.712±0.00 1.414±0.00 2.172±1.70 2.082±0.00 1.717±0.00 5.307±4.68 4.605±0.00 6.488±0.00 5.300±3.53 3.392±2.11 9.778±7.32
ENST00000463423 N/A N/A N/A N/A N/A 4.385±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000464283 N/A N/A N/A N/A N/A 2.310±0.00 N/A 5.553±0.00 N/A 4.011±0.00 6.699±0.00 8.980±0.00 6.467±0.00 9.190±0.00
ENST00000479480 3.097±0.00 N/A 1.459±0.00 N/A N/A 1.747±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000498694 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.488±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004JG CIL_0004JG_0002 CGP 1:40861051-41012565
CIL_0009C0 CIL_0009C0_0001 VISTA 1:40944924-41547265
CIL_000876 CIL_000876_0001 VISTA 1:40945428-41547337

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003883 IDA:IEA CTP synthase activity
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0006139 TAS nucleobase-containing compound metabolic process
GO:0006221 IEA pyrimidine nucleotide biosynthetic process
GO:0006241 IDA CTP biosynthetic process
GO:0006541 IEA glutamine metabolic process
GO:0015949 TAS nucleobase-containing small molecule interconversion
GO:0016020 IDA membrane
GO:0016787 IEA hydrolase activity
GO:0042098 IMP T cell proliferation
GO:0042100 IMP B cell proliferation
GO:0042493 TAS response to drug
GO:0044210 IEA 'de novo' CTP biosynthetic process
GO:0044281 TAS small molecule metabolic process
GO:0055086 TAS nucleobase-containing small molecule metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030700 ctps1a CTP synthase 1a protein_coding Danio_rerio
ENSDARG00000054099 ctps1b CTP synthase 1b protein_coding Danio_rerio
ENSDARG00000087777 ctps1b CTP synthase 1b protein_coding Danio_rerio
ENSMUSG00000028633 Ctps cytidine 5'-triphosphate synthase protein_coding Mus_musculus

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