C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: exosome component 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000171824 EXOSC10 9606 - 1:11066618-11099881 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000304457 EXOSC10-002 11066618-11099869 protein_coding
  ENST00000376936 EXOSC10-001 11066618-11099881 protein_coding
  ENST00000460196 EXOSC10-008 11091503-11099854 nonsense_mediated_decay
  ENST00000469634 EXOSC10-004 11068645-11073026 retained_intron
  ENST00000470611 EXOSC10-009 11074288-11079800 processed_transcript
  ENST00000472078 EXOSC10-010 11079770-11080857 retained_intron
  ENST00000474216 EXOSC10-003 11066621-11081217 retained_intron
  ENST00000478271 EXOSC10-006 11068654-11072395 retained_intron
  ENST00000485606 EXOSC10-011 11080701-11082623 processed_transcript
  ENST00000490565 EXOSC10-005 11066685-11068924 retained_intron
  ENST00000498576 EXOSC10-007 11077009-11077651 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000376936ENST00000474216ENST00000478271ENST00000485606
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000376936 12.184±0.00 12.214±0.00 1.939±0.00 6.599±1.55 7.896±2.60 5.916±0.07 5.425±3.05 9.736±5.58 6.123±0.05 4.866±1.44 8.225±3.24 24.350±15.03 17.824±4.37 26.136±6.73
ENST00000474216 N/A 8.313±0.00 N/A 3.385±0.00 N/A 1.609±0.00 N/A N/A N/A 3.375±0.00 N/A 6.460±0.00 N/A N/A
ENST00000478271 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 78.169±0.00 28.834±0.00 31.657±0.00
ENST00000485606 N/A N/A N/A N/A 15.112±0.00 10.819±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008RU CIL_0008RU_0001 VISTA 1:10491513-11092116
CIL_0008JG CIL_0008JG_0001 VISTA 1:10565145-11165671
CIL_0008JY CIL_0008JY_0001 VISTA 1:10605072-11206087

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000176 IEA nuclear exosome (RNase complex)
GO:0000178 IDA exosome (RNase complex)
GO:0000184 IMP nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000460 IMP maturation of 5.8S rRNA
GO:0000956 IMP nuclear-transcribed mRNA catabolic process
GO:0003676 IEA nucleic acid binding
GO:0003824 IEA catalytic activity
GO:0004532 IDA exoribonuclease activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0006139 IEA nucleobase-containing compound metabolic process
GO:0006396 IEA RNA processing
GO:0008408 IEA 3'-5' exonuclease activity
GO:0009048 IEA dosage compensation by inactivation of X chromosome
GO:0016020 IDA membrane
GO:0035327 IMP transcriptionally active chromatin
GO:0044237 IEA cellular metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0071028 IMP nuclear mRNA surveillance
GO:0071034 IMP CUT catabolic process
GO:0071035 IMP nuclear polyadenylation-dependent rRNA catabolic process
GO:0071044 IMP histone mRNA catabolic process
GO:0071048 IMP nuclear retention of unspliced pre-mRNA at the site of transcription
GO:0090503 IDA RNA phosphodiester bond hydrolysis, exonucleolytic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037708 exosc10 exosome component 10 protein_coding Danio_rerio
ENSMUSG00000017264 Exosc10 exosome component 10 protein_coding Mus_musculus

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